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Endometrial Cancer clinical trials in Orlando, FL

17 studies for Endometrial Cancer are looking for participants at sites in and around Orlando (within about 30 miles). Open a study to see who can join and how to contact the study team.

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Advent Health, Orlando
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • AdventHealth Cancer Institute, Orlando
Ages 19 and older · All sexes · Updated Oct 1, 2026 · NCT06586957

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • AdventHealth Medical Group Oncology Research at Celebration, Kissimmee · 16 mi away
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer

RecruitingObservational study
  • Orlando Health, Orlando
Ages 18 and older · Women · Updated Sep 29, 2026 · NCT05051722

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

RecruitingPhase 1
  • Sara Cannon Research Institute Lake Nona, Orlando
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

RecruitingPhase 3
  • AdventHealth Orlando-AdventHealth Medical Group Gynecological Oncology ( Site 6002), Orlando
Ages 18 and older · Women · Updated Sep 17, 2026 · NCT06952504

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

RecruitingPhase 1/2
  • Florida Cancer Specialists - Lake Nona, Orlando
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07109726

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute - Lake Nona Florida, Orlando
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06293898

Phase 1 Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of ARR-002 in Advanced or Metastatic Ovarian or Endometrial Cancer.

RecruitingPhase 1
  • Sarah Cannon Research Institute at Florida Cancer Specialists, Orlando
Ages 18 and older · Women · Updated Sep 3, 2026 · NCT07755436

A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9

RecruitingPhase 1/2
  • Florida Cancer Specialists, Orlando
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07186842

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • AdventHealth Celebration, Celebration · 17 mi away
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease

RecruitingObservational study
  • ADVENTHEALTH (Data collection only), Orlando
Ages 18 and older · Women · Updated Aug 7, 2026 · NCT04291612

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

RecruitingPhase 3
  • Research Site, Orlando
Ages 18 and older · Women · Updated Jul 29, 2026 · NCT07044336

A Study of LY4175408 in Participants With Advanced Cancer

RecruitingPhase 1
  • Florida Cancer Specialists - Lake Nona - Sarah Cannon Research Institute, Orlando
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT07046923

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

RecruitingPhase 1
  • Dren Investigational Site, Orlando
Ages 18 and older · All sexes · Updated Jan 7, 2026 · NCT06999187

A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.

RecruitingPhase 2
  • Orlando Health, Orlando
Ages 18 to 70 · Women · Updated Oct 30, 2025 · NCT06481592

Endometrial Cancer trials in other cities

Other studies in Orlando

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.