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Colorectal Cancer clinical trials in Omaha, NE

18 studies for Colorectal Cancer are looking for participants at sites in and around Omaha (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Family Communications After Genetic Testing

RecruitingHealthy volunteers welcome
  • Alegent Health Immanuel Medical Center, Omaha
  • Alegent Health Bergan Mercy Medical Center, Omaha
  • Alegent Health Lakeside Hospital, Omaha
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

RecruitingPhase 2
  • Nebraska Medicine-Village Pointe, Omaha
  • University of Nebraska Medical Center, Omaha
  • Nebraska Medicine-Bellevue, Bellevue · 9 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05673148

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Alegent Health Immanuel Medical Center, Omaha
  • Alegent Health Bergan Mercy Medical Center, Omaha
  • Alegent Health Lakeside Hospital, Omaha
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #2, Omaha
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Nebraska Cancer Specialists, Omaha
  • XCancer, Omaha
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07189871

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

RecruitingPhase 1/2
  • Nebraska Cancer Specialists, Omaha
  • University of Nebraska Medical Center, Omaha
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

Zanzalintinib Alone or in Combination With Pembrolizumab and Berahyaluronidase Alfa in Participants With Colorectal Cancer With Molecular Residual Disease

RecruitingPhase 3
  • Oncology Hematology West, PC dba Nebraska Cancer Specialists - Methodist, Omaha
  • Oncology Hematology West, PC dba Nebraska Cancer Specialists - Bergan, Omaha
  • Oncology Hematology West, PC dba Nebraska Cancer Specialists - Legacy, Omaha
  • and 2 more
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07750158

A Study to Investigate CEA-PRIT 2.0 in Participants With Metastatic Colorectal Cancer (mCRC)

RecruitingPhase 1
  • Nebraska Cancer Specialists, Omaha
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07416552

Lead-212 PSV359 Therapy for Patients With Solid Tumors

RecruitingPhase 1/2
  • Nebraska Cancer Specialists, Omaha
Ages 18 to 90 · All sexes · Updated Jul 6, 2026 · NCT06710756

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

RecruitingPhase 1
  • Nebraska Cancer Specialists (Midwest Cancer Center - Legacy), Omaha
  • XCancer Omaha / Urology Cancer Center, Omaha
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05283330

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

RecruitingPhase 3Healthy volunteers welcome
  • Alegent Health Immanuel Medical Center, Omaha
  • Alegent Health Bergan Mercy Medical Center, Omaha
  • Alegent Health Lakeside Hospital, Omaha
  • and 1 more
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Nebraska Cancer Specialists, Omaha
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays

RecruitingObservational study
  • Nebraska Cancer Specialists, Omaha
Ages 18 and older · All sexes · Updated May 6, 2025 · NCT05234177

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Omaha

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.