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Opioid Overdose clinical trials in Boston, MA

12 studies for Opioid Overdose are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Sustaining Recovery for People on Opioid Agonist Treatment With Conversational Agents

Recruiting
  • Office-Based Addiction Treatment (OBAT) Clinic, BMC, Boston
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06732596

A Study of Brenipatide in Participants With Opioid Use Disorder

RecruitingPhase 2
  • Brigham and Women's Hospital, Boston
  • Adams Clinical Boston, Boston
  • Boston Medical Center, Boston
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07420283

Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment.

RecruitingPhase 4
  • Officed Based Addiction Treatment Program, Boston Medical Center, Boston
Ages 18 to 99 · All sexes · Updated Sep 14, 2026 · NCT06323824

Assessing Optimal XRB Initiation Points in Jail

RecruitingPhase 4
  • Tufts University Health Sciences, Boston
All ages · Men · Updated Aug 7, 2026 · NCT06051890

Psilocybin in Cancer Pain Study

RecruitingPhase 2
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06001749

Impact of Federal and State Medications for Opioid Use Disorder (MOUD) Policy Changes During the Pandemic

RecruitingObservational study
  • VA Medical Center, Boston
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT07232641

CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial

RecruitingPhase 3
  • Harvard University- Brigham and Women's Hospital, Boston
Ages 18 to 75 · All sexes · Updated May 6, 2026 · NCT06027099

PrEP and MOUD Rapid Access for Persons Who Inject Drugs: The CHORUS+ Study

Recruiting
  • Boston Medical Center Faster Paths Bridge Clinic, Boston
  • Victory Programs Mobile Prevention Services Van and Navigation Center, Boston
Ages 18 and older · All sexes · Updated Apr 6, 2026 · NCT05769218

Adolescent Outcomes of Post-operative Opioid EXposure

RecruitingObservational study
  • Boston Childrens Hopsital - Division of Addiction Medicine, Boston
Ages 12 to 17 · All sexes · Updated Mar 18, 2026 · NCT06350409

Sensory Outcomes in Active Substance Users

RecruitingObservational study
  • Boston Medical Center/Boston University Medical Campus, Boston
Ages 18 and older · All sexes · Updated Feb 10, 2026 · NCT06639438

Towards Testing the Effectiveness of Recovery Community Centers (RCCs)

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 26, 2025 · NCT07010978

Semaglutide for Helping Opioid Recovery

RecruitingPhase 2
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 26, 2025 · NCT06639464

About Opioid Overdose

Opioid overdose leads to slowing or stopping of breathing and sometimes death. You can take steps to help prevent an overdose, and respond to one with naloxone.

More about Opioid Overdose on MedlinePlus

Opioid Overdose trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.