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Lupus clinical trials in Philadelphia, PA

9 studies for Lupus are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

RecruitingPhase 2
  • Temple University, Philadelphia
Ages 18 to 100 · All sexes · Updated Oct 1, 2026 · NCT05268289

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

RecruitingPhase 3
  • Research Site, Philadelphia
Ages 5 to 17 · All sexes · Updated Sep 30, 2026 · NCT05835310

A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus

RecruitingPhase 3
  • Clinical Research Philadelphia, Philadelphia
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT07438496

CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus

RecruitingPhase 1/2
  • Children's Hospital of Philadelphia, Philadelphia
Ages 10 to 29 · All sexes · Updated Sep 24, 2026 · NCT06839976

A Phase IIa Study of ICG318 CAR-T in Refractory Systemic Lupus Erythematosus With or Without Lupus Nephritis

RecruitingPhase 2
  • Fox Chase Cancer Center- Temple BMT, Philadelphia
Ages 16 to 70 · All sexes · Updated Sep 17, 2026 · NCT07328581

A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants

RecruitingObservational study
  • Local Institution - 0075, Philadelphia
  • Local Institution - 0052, Philadelphia
Ages 16 and older · All sexes · Updated Sep 3, 2026 · NCT07175285

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

RecruitingPhase 1/2
  • Children's Hospital of Philadelphia, Philadelphia
Ages 18 to 65 · All sexes · Updated Aug 26, 2026 · NCT06121297

A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

RecruitingPhase 1
  • Jefferson Einstein Hospital Philadelphia, Philadelphia
Ages 12 to 70 · All sexes · Updated May 22, 2026 · NCT06308978

Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases

RecruitingPhase 2
  • Children's Hospital of Philadelphia, Philadelphia
Ages 8 to 25 · All sexes · Updated Oct 14, 2025 · NCT05029336

About Lupus

Lupus is an autoimmune disease that causes your immune system to attack your healthy tissues and cells. This can cause damage to many parts of your body.

More about Lupus on MedlinePlus

Lupus trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.