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Alzheimer's Disease clinical trials in Chicago, IL

11 studies for Alzheimer's Disease are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

RecruitingPhase 3
  • RE:Cognition (Chicago), Chicago
  • Great Lakes Clinical Trials Chicago d/b/a Flourish Research Andersonville, Chicago
Ages 50 to 90 · All sexes · Updated Sep 21, 2026 · NCT07177352

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

RecruitingPhase 3
  • Great Lakes Clinical Trials - Andersonville, Chicago
Ages 60 to 85 · All sexes · Updated Sep 17, 2026 · NCT06976203

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

RecruitingPhase 3
  • Re:Cognition Health - Chicago, Chicago
Ages 60 to 85 · All sexes · Updated Aug 20, 2026 · NCT06976216

Central Auditory Processing Modulation Underlying Anxiety Reduction Using Clinically Designed Improvisatory Music

Recruiting
  • Northwestern University Feinberg School of Medicine, Chicago
Ages 55 and older · All sexes · Updated Aug 20, 2026 · NCT07775625

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

RecruitingPhase 3
  • John H. Stroger, Jr. Hospital of Cook County, Chicago
  • University of Chicago - Medical Center, Chicago
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

Development of a Home Test for Measuring Blood P-tau217 in Alzheimer's Disease Using the Tasso Lancet Device

RecruitingObservational studyHealthy volunteers welcome
  • Insigth Hospital and Medical Center Chicago, Chicago
Ages 40 to 90 · All sexes · Updated Jul 14, 2026 · NCT07701161

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

RecruitingPhase 3
  • Great Lakes Clinical Trials - Andersonville, Chicago
Ages 55 and older · All sexes · Updated Jul 7, 2026 · NCT07602582

Communication Bridge 3 Study

RecruitingPhase 2
  • University of Chicago - American School Building, Chicago
Ages 18 to 100 · All sexes · Updated Jun 1, 2026 · NCT06191198

Feasibility of Using the Gatorade Sports Science Institute (GSSI) Labs App for Hydration Related Outcomes

RecruitingObservational studyHealthy volunteers welcome
  • Advanced Personalized Ideation Center (API) and Gatorade Sports Science Institute (GSSI), PepsiCo Global R&D - Life Sciences, Chicago
Ages 18 to 65 · All sexes · Updated Jun 5, 2025 · NCT07005895

Alzheimer's National Registry for Treatment and Diagnostics(ALZ-NET)

RecruitingObservational study
  • Full List of Active Sites, Chicago
Ages 18 and older · All sexes · Updated Dec 14, 2023 · NCT06170268

About Alzheimer's Disease

Alzheimer's disease is a brain disorder that slowly destroys memory and thinking skills. It's the most common cause of dementia among older adults.

More about Alzheimer's Disease on MedlinePlus

Alzheimer's Disease trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.