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Colorectal Cancer clinical trials in San Diego, CA

25 studies for Colorectal Cancer are looking for participants at sites in and around San Diego (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

Recruiting
  • Jennifer Moreno Department of Veterans Affairs Medical Cneter, San Diego
Ages 65 to 82 · All sexes · Updated Oct 2, 2026 · NCT05612347

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • University of San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • University of California San Diego Moores Cancer Center, San Diego
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

RecruitingPhase 1
  • ALX Center 9, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07085091

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • UC San Diego McGrath Outpatient Pavilion - Hillcrest, San Diego
  • UC San Diego Medical Center - Hillcrest, San Diego
  • UC San Diego Medical Center - Rancho Bernardo, San Diego
  • and 3 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

RecruitingObservational study
  • University of California San Diego, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

RecruitingPhase 1/2
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

RecruitingPhase 1
  • University of California, San Diego (UCSD) - Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07216105

A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

RecruitingPhase 1
  • UC San Diego Moores Cancer Center, San Diego
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07227168

BAL/BOT/agenT-797 in pMMR CRC With Liver Metastases

RecruitingPhase 2
  • Scripps Clinic Torrey Pines, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07550088

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Sharp Healthcare, San Diego
  • UCSD, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT03526835

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Investigative Site #101, San Diego
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06974110

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

RecruitingPhase 4
  • University of California San Diego, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06562543

Early Detection of Advanced Adenomas and Colorectal Cancer

RecruitingObservational studyHealthy volunteers welcome
  • University of California San Diego, San Diego
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06342440

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • UCSD Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

RecruitingPhase 1
  • University of California San Diego Moores Cancer Center, San Diego
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06917079

Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study

RecruitingObservational study
  • VA San Diego Healthcare System, San Diego, CA, San Diego
Ages 75 and older · All sexes · Updated May 12, 2026 · NCT05994482

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

RecruitingPhase 1/2
  • University of California San Diego (UC San Diego) Health - Jacobs Medical Center - Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06244771

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • UCSD Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT06682793

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

RecruitingPhase 1
  • Moores Cancer Center UC San Diego Health, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Aug 15, 2025 · NCT04429542

A Beta-only IL-2 ImmunoTherapY Study

RecruitingPhase 1/2
  • Sharp Memorial Hospital, San Diego
Ages 18 and older · All sexes · Updated Jul 9, 2025 · NCT05086692

Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer

RecruitingPhase 3
  • Moores Cancer Center - UCSD Health, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Apr 24, 2024 · NCT03659448

Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies

RecruitingPhase 1
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Feb 8, 2024 · NCT04282044

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in San Diego

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.