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Heart Failure clinical trials in Winston-Salem, NC

5 studies for Heart Failure are looking for participants at sites in and around Winston-Salem (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets

RecruitingObservational studyHealthy volunteers welcome
  • Wake Forest University, Winston-Salem
Ages 30 and older · All sexes · Updated Sep 29, 2026 · NCT05873634

Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction

RecruitingObservational studyHealthy volunteers welcome
  • Wake Forest University, Winston-Salem
Ages 30 and older · All sexes · Updated Sep 29, 2026 · NCT06517186

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

RecruitingPhase 3
  • Wake Forest University Health Sciences, Winston-Salem
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT06736574

LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2

RecruitingPhase 3
  • Tenax Investigational Site, Winston-Salem
Ages 18 to 85 · All sexes · Updated Aug 19, 2026 · NCT07288398

BOOST: Blended Onsite and Offsite Structured Exercise Training and Coaching

Recruiting
  • Wake Forest University Health Sciences, Winston-Salem
Ages 55 and older · All sexes · Updated May 26, 2026 · NCT07413198

About Heart Failure

Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.

More about Heart Failure on MedlinePlus

Heart Failure trials in other cities

Other studies in Winston-Salem

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.