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Heart Failure clinical trials in Houston, TX
35 studies for Heart Failure are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.
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Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
RecruitingPhase 2/3
- Texas Children's Hospital ( Site 0039), Houston
Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure
Recruiting
- Baylor College of Medicine, Houston
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
RecruitingPhase 3
- The Methodist Hospital Research Institute, Houston
Left vs Left Randomized Clinical Trial
Recruiting
- Baylor College of Medicine, Houston
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Recruiting
- CHI St. Luke's Health Baylor College of Medicine Medical Center, Houston
- Houston Methodist, Houston
- UTHealth Memorial Hermann, Houston
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
RecruitingObservational study
- Houston, Houston
A Study of LY3971297 in Participants With Heart Failure
RecruitingPhase 1
- Houston Methodist Hospital, Houston
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
RecruitingPhase 3
- CHI St. Luke's Health Baylor College of Medicine Medical Center, Houston
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
RecruitingPhase 3
- East Texas Cardiology PA, Houston
- Biopharma Informatic, Houston
- Orion Medical, Houston
- and 3 more
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
RecruitingPhase 3
- Texas Children's Hospital - Cardiology, Houston
Cardiogenic Shock Working Group Registry
RecruitingObservational study
- Houston Methodist Hospital, Houston
Assessment of CCM in HF With Higher Ejection Fraction
Recruiting
- Baylor College of Medicine, Houston
- Houston Methodist, Houston
- Memorial Hermann Texas Medical Center, Houston
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
RecruitingPhase 3
- Research Site, Houston
- Research Site, Houston
- Research Site, Houston
- and 2 more
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
RecruitingPhase 3
- Texas Children's Hospital - Cardiology, Houston
A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
RecruitingPhase 2
- Local Institution - 19, Houston
- Local Institution - 20, Houston
- Local Institution - 21, Houston
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
RecruitingPhase 3
- Research Site, Houston
CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
Recruiting
- Michael E. DeBakey VA Medical Center, Houston, TX, Houston
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
RecruitingPhase 2
- East Texas Cardiology PA, Houston
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
RecruitingPhase 3
- Research Site, Houston
- Research Site, Houston
- Research Site, Humble · 17 mi away
BiVACOR® Total Artificial Heart Early Feasibility Study
Recruiting
- Texas Heart Institute / Baylor St. Luke's Medical Center, Houston
A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
RecruitingPhase 3
- CON-10085, Houston, TX, Houston
- Houston, TX Investigative Site CON-10320, Houston
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
RecruitingPhase 3
- Houston, TX Investigative Site 10085, Houston
Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation
RecruitingObservational study
- Methodist DeBakey Heart and Vascular Center, Houston
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
RecruitingPhase 2
- Center for Advanced Heart Failure, Houston
Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs
RecruitingObservational study
- Texas Children's Hospital, Houston
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Recruiting
- Texas Heart Institute, Houston
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
RecruitingObservational study
- The Methodist Hospital, Methodist Cancer Cencer, Houston
- BI Research Center, Houston
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
RecruitingPhase 3
- East Texas Cardiology PA, Houston
- Victorium Clinical Research, Houston
- Main Heart Clinic, Houston
- and 1 more
A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
RecruitingPhase 3
- FIN-10085, Houston, TX, Houston
18F-mFBG Imaging for Myocardial Sympathetic Innervation
RecruitingPhase 2
- UT Health Houston, Houston
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
Recruiting
- Baylor/Texas Heart, Houston
Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)
RecruitingObservational study
- Baylor College of Medicine, Houston
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Recruiting
- Houston Healthcare Medical Center, Houston
Study Assessing Left Ventricular Administration of a Genetic Medicine Directing Organ Regeneration in Heart Failure
RecruitingPhase 1
- Texas Heart Institute, Houston
HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry
RecruitingObservational study
- Houston Methodist DeBakey Heart and Vascular Center, Houston
About Heart Failure
Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.
More about Heart Failure on MedlinePlus
Heart Failure trials in other cities
- New York City, NY51 studies
- Boston, MA46 studies
- Dallas, TX42 studies
- Cleveland, OH31 studies
- Philadelphia, PA31 studies
- San Francisco, CA29 studies
- Chicago, IL28 studies
- Durham, NC25 studies
- Kansas City, MO25 studies
- St. Louis, MO24 studies
- Indianapolis, IN24 studies
- Atlanta, GA23 studies
Other studies in Houston
- Non-Small Cell Lung Cancer143 studies
- Breast Cancer126 studies
- Cancer (all types)124 studies
- Colorectal Cancer101 studies
- Metastatic Cancer100 studies
- Ovarian Cancer90 studies
- Acute Myeloid Leukemia88 studies
- Lung Cancer78 studies
- Prostate Cancer73 studies
- Endometrial Cancer69 studies
- Melanoma61 studies
- Pancreatic Cancer59 studies
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.