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Cancer (all types) clinical trials in Boston, MA

86 studies for Cancer (all types) are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Distance-Based Exercise to Preserve Function and Prevent Disability

Recruiting
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884

A Study of ASP3082 in Adults With Advanced Solid Tumors

RecruitingPhase 1
  • Beth Israel Deaconess Medical Center, Boston
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05382559

A First-in-Human Study of KK2223 in Participants With Relapsed or Refractory T Cell Non-Hodgkin Lymphoma

RecruitingPhase 1
  • Beth Israel Deaconess Medical Center - Research, Boston
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07192471

uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

RecruitingObservational study
  • Mass General Brigham, Boston
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05874921

A Phase 1 Study of IM-1617 in Participants With Advanced Cancer

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07578571

A Study of PHN-012 in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • PHN-012-001 Site, Boston
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874

A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism

RecruitingPhase 3
  • Investigative Site, Boston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06881992

A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)

RecruitingPhase 1/2
  • Dana Farber Cancer Center ( Site 4013), Boston
1 Month – 17 Years · All sexes · Updated Sep 25, 2026 · NCT07630974

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

RecruitingPhase 3
  • Dana Farber/Harvard Cancer Center, Boston
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06901531

Multidisciplinary Intervention for Adults With Chronic Graft-versus-host Disease

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06910969

Pan Tumor Rollover Study

RecruitingPhase 2
  • Dana_Farber Cancer Institute (DFCI), Boston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT03899155

Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)

RecruitingPhase 3
  • Beth Israel Deaconess Medical Center ( Site 0107), Boston
  • Dana-Farber Cancer Institute ( Site 0105), Boston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07405164

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

RecruitingPhase 3
  • Dana-Farber Cancer Institute /ID# 279690, Boston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07365241

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

RecruitingPhase 2/3
  • Massachusetts General Hospital / Dana-Farber Cancer Institute, Boston
All ages · All sexes · Updated Sep 18, 2026 · NCT03435796

A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)

RecruitingPhase 1/2
  • Dana-Farber Cancer Institute ( Site 3013), Boston
1 Month – 17 Years · All sexes · Updated Sep 17, 2026 · NCT06941272

Statins to Prevent Cancer Associated Blood Clots

RecruitingPhase 4
  • Beth Isreal Deaconess Medical Center, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07303816

Proof-of-Concept Testing of the Cardiovascular Health Equity Through Food (CHEF) Intervention in Childhood Cancer Survivors

Recruiting
  • Boston Children's Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Up to age 18 · All sexes · Updated Sep 16, 2026 · NCT06609473

ACTIVATE: AI-driven Clinical-trial Trial-Information and Viability Assessment Tool for EHRs

Recruiting
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07232043

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

RecruitingPhase 2
  • Dana Farber Cancer Institute, Boston
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

RecruitingPhase 2
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04996875

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

RecruitingPhase 1/2
  • Research Site, Boston
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT05123482

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

RecruitingPhase 1/2
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05386108

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • Boston Medical Center, Boston
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

RecruitingObservational study
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534

Lurbinectedin in FET-Fused Tumors

RecruitingPhase 1/2
  • Dana-Farber Cancer Institute, Boston
Ages 10 and older · All sexes · Updated Sep 2, 2026 · NCT05918640

Prostate Active Surveillance Study

RecruitingObservational study
  • Beth Israel Deaconess Medical Center/Harvard Medical School, Boston
Ages 21 and older · Men · Updated Sep 2, 2026 · NCT00756665

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Massachusetts General Hospital (MG), Boston
Ages 18 to 99 · All sexes · Updated Sep 1, 2026 · NCT06983743

A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07075185

BRIDGE-SIC Efficacy Trial

Recruiting
  • Brigham and Women's Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07735442

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Massachusetts General Hospital Cancer Center, Boston
  • Dana-Farber Cancer Institute, Boston
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Abatacept in Immune Checkpoint Inhibitor Myocarditis

RecruitingPhase 3
  • Massachusetts General Hospital, Boston
  • Beth Israel Deaconess Medical Center, Boston
  • Boston Medical Center, Boston
  • and 1 more
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05335928

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT04104776

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies

RecruitingPhase 1
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06759649

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Massachusetts General Hospital Cancer Center, Boston
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer

RecruitingPhase 1
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · Men · Updated Aug 10, 2026 · NCT06067841

A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

RecruitingPhase 2
  • Dana-Farber Cancer Institute, Boston
Ages 1 to 39 · All sexes · Updated Aug 7, 2026 · NCT05999994

A Study of [18F]LY4214835 in Healthy Volunteers and Participants With Cancer

RecruitingPhase 1Healthy volunteers welcome
  • Boston Medical Center, Boston
  • Massachusetts General Hospital (MGH), Charlestown · 1 mi away
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07258836

Sparsentan for the Treatment of VEGF Signaling Pathway Inhibitor-Associated Proteinuria

RecruitingPhase 1
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07224776

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 12 and older · All sexes · Updated Jul 14, 2026 · NCT05533697

A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors

RecruitingPhase 1
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06997029

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

The STOP-MED CTRCD Trial

RecruitingPhase 4
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06183437

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

RecruitingPhase 1/2
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT06162221

A Study to Evaluate the Safety,Tolerability, Pharmacokinetics and Clinical Activity of Mocertatug Rezetecan for Injection in Participants With Advanced Solid Tumors (BEHOLD-1)

RecruitingPhase 1
  • GSK Investigational Site, Boston
  • GSK Investigational Site, Boston
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06431594

Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Beth Israel Deaconess Medical Center, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT06993844

Childhood Cancer Survivor Study

RecruitingObservational studyHealthy volunteers welcome
  • Dana-Farber Cancer Institute, Boston
All ages · All sexes · Updated Jun 17, 2026 · NCT01120353

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

Recruiting
  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

RecruitingPhase 1
  • Research Site, Boston
  • Research Site, Boston
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569

Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

RecruitingPhase 1
  • Beth Israel Deaconess Medical Center /ID# 252009, Boston
  • Dana-Farber Cancer Institute /ID# 249642, Boston
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT04777994

Multisite Implementation of COMPRENDO

RecruitingHealthy volunteers welcome
  • Dana Farber Cancer Institute/Boston Children's Hospital, Boston
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06055296

A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

RecruitingPhase 1
  • Mass General Brigham Cancer Institute, Boston
  • Dana Farber Cancer Institute, Boston
Ages 16 and older · All sexes · Updated Jun 2, 2026 · NCT07197554

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

RecruitingPhase 1/2
  • Massachusetts General Hospital,, Boston
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116

A Study of GSK5764227 in Participants With Advanced Solid Tumors (EMBOLD)

RecruitingPhase 1
  • GSK Investigational Site, Boston
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06551142

Video Inspired Discussions About Ethical Outcomes in Pediatrics

Recruiting
  • Dana Farber Cancer Institute, Boston
All ages · All sexes · Updated May 14, 2026 · NCT06786104

On-Trac: An Online Intervention for Cancer Survivors Managing Anxiety

RecruitingMentions payment for participants
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT07305740

ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT03686124

Study of the CDK4/6 Inhibitor Abemaciclib in Solid Tumors Harboring Genetic Alterations in Genes Encoding D-Type Cyclins or Amplification of CDK4 or CDK6

RecruitingPhase 2
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Apr 29, 2026 · NCT03310879

Intraoperative Tumor Margin Identification With ICG Dye Imaging

RecruitingPhase 2
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT04752137

CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

RecruitingPhase 1/2
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT03328078

Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TGW101 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT06959706

Suprachoroidal Administration in Subjects With Metastases to the Choroid

RecruitingPhase 2
  • Massachusetts Eye and Ear, Boston
Ages 18 and older · All sexes · Updated Mar 13, 2026 · NCT06643884

Supportive Care Intervention for Outpatient Stem Cell Transplant Patients

Recruiting
  • Dana-Farber Cancer Institute, Boston
Ages 19 and older · All sexes · Updated Mar 6, 2026 · NCT06564233

Positron Emission Tomography (PET) Imaging of Thrombosis

RecruitingPhase 1Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 85 · All sexes · Updated Feb 27, 2026 · NCT03830320

Primary Tumor Research and Outcomes Network

RecruitingObservational study
  • Massachusetts General Hospital, Boston
All ages · All sexes · Updated Feb 25, 2026 · NCT02790983

Pembrolizumab, Ibrutinib and Rituximab in PCNSL

RecruitingPhase 1/2
  • Dana Farber Cancer Institute, Boston
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Feb 20, 2026 · NCT04421560

Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy

Recruiting
  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Ages 18 and older · All sexes · Updated Feb 19, 2026 · NCT02984761

PediRISE Feasibility

Recruiting
  • Boston Children's Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Up to age 17 · All sexes · Updated Feb 10, 2026 · NCT06283251

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

RecruitingPhase 2
  • Dana-Farber Cancer Institute /ID# 230061, Boston
Ages 18 and older · All sexes · Updated Feb 9, 2026 · NCT04895436

A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers

Recruiting
  • Massachusetts General Hospital Cancer Center, Boston
Ages 25 to 39 · All sexes · Updated Jan 12, 2026 · NCT06172907

A Study of YL242 in Subjects With Advanced Solid Tumors

RecruitingPhase 1/2
  • US-204, Boston
Ages 18 and older · All sexes · Updated Dec 24, 2025 · NCT07197827

Targeted Therapy to Increase RAI Uptake in Metastatic DTC

RecruitingObservational study
  • Boston Children's Hospital, Boston
Ages 0 and older · All sexes · Updated Nov 14, 2025 · NCT05024929

Eliminating Barriers to Colorectal Cancer Screening Using Rapid Cycle Testing: A Pilot Study

RecruitingHealthy volunteers welcome
  • Codman Square Health Center, Boston
  • East Boston Neighborhood Health Center, East Boston · 2 mi away
Ages 18 and older · All sexes · Updated Nov 14, 2025 · NCT05524428

Childhood Cancer Predisposition Study (CCPS)

RecruitingObservational study
  • Dana Farber Cancer Institute, Boston
All ages · All sexes · Updated Oct 29, 2025 · NCT04511806

BMT-CARE: Psychosocial Intervention for Transplant Caregivers

Recruiting
  • Massachusetts General Hospital Cancer Center, Boston
Ages 18 and older · All sexes · Updated Oct 15, 2025 · NCT06472089

Developing a Test of Uterine Lavage for the Detection of Ovarian Cancer

RecruitingObservational study
  • Massachusetts General Hospital, Boston
Ages 30 and older · Women · Updated Sep 16, 2025 · NCT04794322

Bladder Fiducial Markers and Multiparametric-MRI (Mp-MRI) to Optimize Bladder Chemo-radiotherapy

Recruiting
  • Harvard School of Medicine/Massachusetts General Hospital (MGH), Boston
Ages 18 and older · All sexes · Updated Aug 14, 2025 · NCT04442724

Evaluating Informatics-assisted Immune-related Adverse Event Detection to Improve Registration Onto a Biorepository

RecruitingPhase 1/2
  • Brigham and Women's Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
All ages · All sexes · Updated Jun 19, 2025 · NCT06789601

Communicating Uncertainties Associated With the Benefits and Risks of New Cancer Drugs

RecruitingHealthy volunteers welcome
  • Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston
Ages 18 and older · All sexes · Updated May 30, 2025 · NCT06997185

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Feb 13, 2025 · NCT05669430

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Nov 15, 2024 · NCT04787042

Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer

RecruitingPhase 3
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Apr 24, 2024 · NCT03659448

About Cancer (all types)

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Cancer (all types) trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.