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Prostate Cancer clinical trials in Denver, CO

19 studies for Prostate Cancer are looking for participants at sites in and around Denver (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Rocky Mountain Cancer Center, Denver
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

RecruitingPhase 3
  • Kaiser Permanente-Franklin, Denver
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT06931340

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute at HealthOne, Denver
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • AdventHealth Porter, Denver
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

RecruitingPhase 1/2
  • Sarah Cannon Research Institute 1, Denver
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06800313

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

RecruitingPhase 3
  • Rocky Mountain Cancer Centers, Denver
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

RecruitingPhase 3
  • Rocky Mountain Cancer Centers, Denver
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06855277

A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate Cancer

RecruitingPhase 1/2
  • GSK Investigational Site, Denver
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06990880

Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer

RecruitingPhase 1
  • Rocky Mountain Cancer Centers, Denver
  • United States Oncology Regulatory Affairs Corporate Office, Denver
  • US Oncology Research Investigational Products Center, Denver
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT07493512

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Kaiser Permanente-Franklin, Denver
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

RecruitingPhase 1
  • Sarah Cannon Research Institute - Denver DDU, Denver
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

RecruitingPhase 3
  • UCHealth - Cherry Creek, Denver
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Pragmatic Trial of Metformin for Glucose Intolerance or Increased BMI in Prostate Cancer Patients

RecruitingEarly phase 1
  • UCHealth-Metro Denver, Denver
Ages 18 and older · Men · Updated Jun 2, 2026 · NCT05515978

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Denver
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

RecruitingPhase 2
  • Porter Adventist Hospital, Denver
Ages 18 and older · Men · Updated Jan 29, 2026 · NCT05806515

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Denver
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

RecruitingPhase 3
  • Porter Adventist Hospital, Denver
Ages 18 and older · Men · Updated Sep 11, 2025 · NCT03678025

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Denver

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.