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HIV clinical trials in San Francisco, CA

15 studies for HIV are looking for participants at sites in and around San Francisco (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

RecruitingPhase 1Healthy volunteers welcome
  • Bridge HIV CRS, San Francisco
Ages 18 to 60 · All sexes · Updated Sep 18, 2026 · NCT06665646

SCOPE: Observational Study of the Consequences of the Protease Inhibitor Era

RecruitingObservational study
  • San Francisco General Hospital, San Francisco
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT00187512

Study of Lenacapavir, Teropavimab, and Zinlirvimab Versus Cabotegravir and Rilpivirine in Virologically Suppressed Adults With HIV-1 on Oral Daily Antiretroviral Therapy

RecruitingPhase 3
  • Optimus Medical Group, San Francisco
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT07682961

A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV

RecruitingPhase 2
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07143968

Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

Recruiting
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jun 22, 2026 · NCT06263426

Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

RecruitingObservational study
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT05663502

Menopausal HT for Women Living With HIV (HoT)

RecruitingPhase 4
  • 801 University of California, San Francisco HIV/AIDS CRS, San Francisco
Ages 40 to 60 · Women · Updated May 22, 2026 · NCT06856174

CAR-T Cells for HIV Infection

RecruitingPhase 1/2
  • Zuckerberg San Francisco General, San Francisco
Ages 18 to 65 · All sexes · Updated Apr 9, 2026 · NCT04648046

SCOPE Analytic Treatment Interruption Protocol

Recruiting
  • University of California San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jan 23, 2026 · NCT04359186

Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)

RecruitingPhase 2
  • San Francisco General Hospital, San Francisco
Ages 40 and older · All sexes · Updated Dec 17, 2025 · NCT05488431

Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health

RecruitingPhase 1Healthy volunteers welcome
  • Bridge HIV, San Francisco Department of Public Health, San Francisco
Ages 18 to 55 · All sexes · Updated Sep 25, 2025 · NCT06796686

Feasibility of HPV Testing With Mail-delivered Sample Collection Kits

RecruitingObservational study
  • University of California, San Francisco, San Francisco
Ages 35 and older · All sexes · Updated Aug 1, 2025 · NCT07087145

Text Education About Cardiovascular Health and HIV (TEACH-HIV)

Recruiting
  • Zuckerberg San Francisco General Hospital, San Francisco
  • University of California San Francisco, San Francisco
Ages 40 and older · All sexes · Updated Jun 8, 2025 · NCT05642858

Imaging Immune Activation in HIV by PET-MR

RecruitingPhase 2
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Oct 24, 2024 · NCT03684655

Comparing Mobile Health Strategies to Improve Pre-exposure Prophylaxis Use (PrEP) for HIV Prevention

RecruitingHealthy volunteers welcome
  • San Francisco AIDS Foundation, San Francisco
Ages 15 and older · All sexes · Updated Sep 28, 2022 · NCT04855773

About HIV

HIV (human immunodeficiency virus) attacks the body’s immune system. There is no cure but it can be treated with medicines. To know if you have HIV, get tested.

More about HIV on MedlinePlus

HIV trials in other cities

Other studies in San Francisco

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.