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Prostate Cancer clinical trials in Minneapolis, MN

23 studies for Prostate Cancer are looking for participants at sites in and around Minneapolis (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Abbott-Northwestern Hospital, Minneapolis
  • Hennepin County Medical Center, Minneapolis
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • Health Partners Frauenshuh Cancer Center, Saint Louis Park · 5 mi away
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • Hennepin County Medical Center, Minneapolis
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer

RecruitingPhase 1
  • University Of Minnesota, Minneapolis
Ages 18 and older · Men · Updated Sep 28, 2026 · NCT06095089

Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1
  • M Health Fairview Clinics and Surgery Center, Minneapolis
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06801236

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

RecruitingPhase 3
  • HealthPartners Cancer Research Center-HealthPartners Frauenshuh Cancer Center ( Site 0072), Saint Louis Park · 5 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

RecruitingPhase 3
  • Minnesota Oncology Hematology PA, Minneapolis
  • University of Minnesota Medical Center Fairview, Minneapolis
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

RecruitingPhase 2
  • Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT04038502

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

RecruitingPhase 3
  • HealthPartners Cancer Research Center-HealthPartners Frauenshuh Cancer Center ( Site 0032), Saint Louis Park · 5 mi away
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

RecruitingPhase 3
  • Abbott-Northwestern Hospital, Minneapolis
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Minneapolis VA Medical Center, Minneapolis
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

RecruitingPhase 1/2
  • Research Site, Minneapolis
Ages 18 to 99 · Men · Updated Aug 27, 2026 · NCT07590934

A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate or Darolutamide

RecruitingPhase 2
  • Masonic Cancer Center, Minneapolis
Ages 18 and older · Men · Updated Aug 21, 2026 · NCT06844383

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

RecruitingPhase 3
  • Abbott-Northwestern Hospital, Minneapolis
  • Hennepin County Medical Center, Minneapolis
  • Health Partners Inc, Minneapolis
  • and 1 more
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • M Health Fairview University of Minnesota Medical Center, Minneapolis
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

RecruitingPhase 1
  • University of Minnesota Medical Center, Minneapolis
Ages 18 to 100 · Men · Updated Aug 13, 2026 · NCT05519449

Study of ORIC-944 in Patients With Metastatic Prostate Cancer

RecruitingPhase 1
  • Minnesota Oncology Hematology, Minneapolis
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT05413421

Axelopran for Advanced Cancer in Patients Receiving Opioids

RecruitingPhase 2
  • HealthPartners Frauenshuh Cancer Research Center, Saint Louis Park · 5 mi away
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT07354919

Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

RecruitingPhase 3
  • Abbott-Northwestern Hospital, Minneapolis
  • Hennepin County Medical Center, Minneapolis
  • Health Partners Inc, Minneapolis
  • and 1 more
Ages 18 and older · Men · Updated Jan 22, 2026 · NCT06470243

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Allina Health Cancer Institute, Minneapolis
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

Vitamin D for Prostate Endocrine Therapy

RecruitingPhase 3
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 50 and older · Men · Updated Jan 15, 2026 · NCT05838716

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

RecruitingPhase 3
  • Hennepin County Medical Center, Minneapolis
  • Health Partners Inc, Minneapolis
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 18 and older · Men · Updated Sep 11, 2025 · NCT03678025

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Minneapolis

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.