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Heart Diseases clinical trials in Chicago, IL

9 studies for Heart Diseases are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

ELEVATE-HFpEF Clinical Study

Recruiting
  • The University of Chicago Medical Center, Chicago
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841

Transition to KPL-387 Monotherapy Dosing & Administration Study

RecruitingPhase 2
  • Investigational Site 013, Chicago
Ages 18 to 80 · All sexes · Updated Sep 30, 2026 · NCT07288216

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
  • Northwestern Memorial Hospital, Chicago
  • Rush University Medical Center, Chicago
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • Advocate Christ Medical Center, Chicago
  • Northwestern University, Chicago
  • University of Chicago, Chicago
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

RecruitingPhase 3
  • John H. Stroger, Jr. Hospital of Cook County, Chicago
  • University of Chicago - Medical Center, Chicago
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • University of Chicago, Chicago
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

Recruiting
  • University of Chicago, Chicago
Ages 18 and older · Women · Updated Apr 1, 2026 · NCT04124120

The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing

RecruitingObservational studyHealthy volunteers welcome
  • University of Chicago Medical Center, Chicago
Ages 18 and older · All sexes · Updated Mar 4, 2026 · NCT01280825

PARTNER 3 Trial - Aortic Valve-in-Valve

Recruiting
  • Northwestern University Hospital, Chicago
  • Rush University Medical Center, Chicago
All ages · All sexes · Updated May 10, 2024 · NCT03003299

About Heart Diseases

Heart disease is the leading cause of death in the U.S. Learn about the different types of heart diseases, and what you can do to try to prevent them.

More about Heart Diseases on MedlinePlus

Heart Diseases trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.