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Overweight clinical trials in St. Louis, MO

16 studies for Overweight are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Effects of Pistachios on Postprandial Metabolic Responses in Adults With Overweight or Obesity

Recruiting
  • Saint Louis University, St Louis
Ages 18 to 35 · All sexes · Updated Oct 2, 2026 · NCT07853898

Two-Week Stair-Climbing Exercise Snacks and Metabolic Health in Adults With Overweight or Obesity: A Pilot Study

RecruitingHealthy volunteers welcome
  • Saint Louis University, St Louis
Ages 18 to 35 · All sexes · Updated Sep 30, 2026 · NCT07849439

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

RecruitingPhase 3
  • Amicis Centers of Clinical Research, St Louis
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07668414

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

RecruitingPhase 3
  • Washington University School of Medicine, St Louis
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

RecruitingPhase 3
  • Sundance Clinical Research, St Louis
Ages 6 to 17 · All sexes · Updated Sep 24, 2026 · NCT06672549

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

RecruitingPhase 3
  • Washington University School of Medicine, St Louis
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

RecruitingPhase 3
  • Research Site, St Louis
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

RecruitingPhase 3
  • Clayton Sleep Institute - St. Louis - Tesson Ferry Road, St Louis
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07369011

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

RecruitingPhase 3
  • Saint Louis Heart and Vascular PC, St Louis
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

RecruitingPhase 3
  • AURORA-1 Clinical Site, St Louis
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743463

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

RecruitingPhase 3
  • AURORA-2 Clinical Site, St Louis
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, St Louis
  • ACCOMPLISH-2 Research Site, Hazelwood · 14 mi away
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

RecruitingPhase 3
  • ACCOMPLISH-1 Research Site, St Louis
  • ACCOMPLISH-1 Research Site, Hazelwood · 14 mi away
Ages 18 to 79 · All sexes · Updated Aug 10, 2026 · NCT07654361

Advancing Biopsychosocial Care Training Initiative

RecruitingHealthy volunteers welcome
  • Washington University School of Medicine, St Louis
Ages 5 and older · All sexes · Updated Aug 10, 2026 · NCT07049861

Effect of Ketone Esters on Liver Fat Content and Metabolic Function

RecruitingPhase 2Healthy volunteers welcome
  • Washington University School of Medicine, St Louis
Ages 18 to 40 · All sexes · Updated Jul 15, 2026 · NCT07097506

Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)

RecruitingObservational studyHealthy volunteers welcome
  • Washington University School of Medicine, St Louis
Ages 12 to 17 · All sexes · Updated Dec 18, 2025 · NCT05277558

Overweight trials in other cities

Other studies in St. Louis

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.