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Head and Neck Squamous Cell Carcinoma clinical trials in Orlando, FL

16 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in and around Orlando (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #48, Celebration · 17 mi away
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

RecruitingPhase 3
  • AdventHealth Medical Group Oncology and Hematology at Orlando, Orlando
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07276399

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

RecruitingPhase 3
  • AdventHealth Orlando, Orlando
Ages 60 and older · All sexes · Updated Sep 25, 2026 · NCT04892173

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

RecruitingPhase 1
  • Sara Cannon Research Institute Lake Nona, Orlando
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

RecruitingPhase 1/2
  • Florida Cancer Specialists - Lake Nona, Orlando
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07109726

SMP-3124LP in Adults With Advanced Solid Tumors

RecruitingPhase 1/2
  • Advent Health, Celebration · 17 mi away
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06526819

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute (Lake Nona), Orlando
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT03526835

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

RecruitingPhase 1/2
  • Clermont Oncology Center, Clermont · 24 mi away
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

A Phase 1 of CTX-8371 in Patients With Advanced Malignancies

RecruitingPhase 1
  • Florida Cancer Specialists - Lake Nona, Orlando
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT06150664

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

RecruitingPhase 1
  • Florida Cancer Specialists, Orlando
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

RecruitingPhase 3
  • AdventHealth Medical Group Oncology & Hematology at Orlando, Orlando
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06064877

A Study of DB-1310 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute at Florida Cancer Specialists, Orlando
Ages 18 and older · All sexes · Updated Apr 6, 2026 · NCT05785741

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Florida Cancer Specialists-Lake Nona, Orlando
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

RecruitingPhase 1
  • Dren Investigational Site, Orlando
Ages 18 and older · All sexes · Updated Jan 7, 2026 · NCT06999187

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 137, Orlando
  • Research Site 118, Celebration · 17 mi away
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

Head and Neck Squamous Cell Carcinoma trials in other cities

Other studies in Orlando

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.