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Major Depressive Disorder clinical trials in St. Louis, MO
7 studies for Major Depressive Disorder are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.
Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →
Lumateperone for Late-Life Depression
RecruitingPhase 3
- Washington University School of Medicine, St Louis
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
RecruitingPhase 2
- Seaport Investigator Site, St Louis
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
Recruiting
- Washington University School of Medicine, St Louis
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
RecruitingPhase 3
- Arch Clinical Trials, LLC, St Louis
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
RecruitingPhase 3
- Arch Clinical Trials, St Louis
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
RecruitingPhase 3
- Tekton Research, St Louis
NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits
RecruitingPhase 1Healthy volunteers welcome
- Washington University School of Medicine, St Louis
Major Depressive Disorder trials in other cities
- New York City, NY37 studies
- Boston, MA31 studies
- Atlanta, GA25 studies
- Philadelphia, PA23 studies
- Orlando, FL19 studies
- Miami, FL18 studies
- Tampa, FL17 studies
- Chicago, IL17 studies
- Houston, TX16 studies
- San Diego, CA16 studies
- Little Rock, AR14 studies
- Austin, TX13 studies
Other studies in St. Louis
- Non-Small Cell Lung Cancer73 studies
- Breast Cancer64 studies
- Metastatic Cancer54 studies
- Colorectal Cancer50 studies
- Prostate Cancer46 studies
- Cancer (all types)46 studies
- Lung Cancer39 studies
- Ovarian Cancer38 studies
- Pancreatic Cancer33 studies
- Endometrial Cancer29 studies
- Head and Neck Squamous Cell Carcinoma28 studies
- Heart Failure26 studies
From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.