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Sickle Cell Disease clinical trials in Atlanta, GA

22 studies for Sickle Cell Disease are looking for participants at sites in and around Atlanta (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)

RecruitingPhase 1
  • Emory University, Atlanta
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07187973

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

RecruitingPhase 3
  • Children's Healthcare Atlanta, Atlanta
Ages 2 and older · All sexes · Updated Sep 18, 2026 · NCT06609226

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

RecruitingPhase 3
  • Children's Healthcare Atlanta, Atlanta
Ages 12 and older · All sexes · Updated Sep 17, 2026 · NCT06612268

Assessing Molecular Mechanisms and Effects of Music Therapy in Youth With Sickle Cell Disease Using Single-cell RNA-sequencing

Recruiting
  • Children's Healthcare of Atlanta, Atlanta
Ages 8 to 18 · All sexes · Updated Sep 10, 2026 · NCT07562451

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

RecruitingPhase 1/2Healthy volunteers welcome
  • Winship Cancer Institute of Emory University, Atlanta
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06481306

A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD

RecruitingPhase 2/3
  • Children's Center for Advanced Pediatrics, Atlanta
Ages 12 and older · All sexes · Updated Aug 18, 2026 · NCT05431088

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

RecruitingObservational study
  • Comprehensive Bleeding Disorders Center at Emory University and Children's Healthcare of Atlanta, Atlanta
  • Emory/Children's Health Care of Atlanta, Atlanta
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628

Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

RecruitingPhase 2
  • Arthur M. Blank Hospital-Children's Healthcare of Atlanta, Atlanta
Ages 12 and older · All sexes · Updated Aug 14, 2026 · NCT06699849

Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)

RecruitingPhase 2
  • Arthur M. Blank Hospital- Children's Healthcare of Atlanta, Atlanta
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07224360

Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease

RecruitingPhase 1/2
  • Children's Healthcare fo Atlanta at Hughes Spalding, Atlanta
  • Children's Healthcare of Atlanta at Arthur M. Blank Hospital, Atlanta
Ages 7 to 21 · All sexes · Updated Jul 29, 2026 · NCT02447874

Cooperative Assessment of Late Effects for SCD Curative Therapies

RecruitingObservational study
  • Emory University School of Medicine, Atlanta
Ages 4 to 65 · All sexes · Updated Jul 27, 2026 · NCT05153967

Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease

RecruitingPhase 1/2
  • Children's Healthcare of Atlanta, Atlanta
Ages 12 to 45 · All sexes · Updated Jun 4, 2026 · NCT07252050

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

RecruitingObservational study
  • Children's Healthcare of Atlanta (MRD-HCT), Atlanta
Ages 3 to 20 · All sexes · Updated Jun 4, 2026 · NCT06941389

Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease

RecruitingPhase 4
  • Emory University, Atlanta
Ages 18 to 50 · Women · Updated May 28, 2026 · NCT06665997

A Socio-ecological Approach for Improving Self-management in Adolescents With SCD

Recruiting
  • Children's Healthcare of Atlanta, Atlanta
Ages 13 to 21 · All sexes · Updated May 11, 2026 · NCT06290401

Study of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease

RecruitingPhase 3
  • Site # 8400006, Atlanta
  • Site # 8400002, Atlanta
Ages 2 to 17 · All sexes · Updated Apr 15, 2026 · NCT07247188

Prophylactic Transfusion In Pregnant in Women With Sickle Cell Disease

RecruitingPhase 4Healthy volunteers welcome
  • Grady Health System, Atlanta
Ages 18 and older · Women · Updated Feb 18, 2026 · NCT06979492

A Long-term Follow-up Study in Patients Who Received BEAM-101

RecruitingObservational study
  • Children's Healthcare of Atlanta - Aflac Cancer and Blood Disorders Center- Egleston, Atlanta
Ages 14 to 37 · All sexes · Updated Jan 28, 2026 · NCT07373639

Trans-auricular Nerve Stimulation as an Innovative Approach to the Treatment of Pain in Pediatric Patients Suffering From Sickle Cell Disease

Recruiting
  • Children's Hospital of Atlanta: Eagelston, Atlanta
Ages 7 to 18 · All sexes · Updated Jan 26, 2026 · NCT07090668

Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain

Recruiting
  • Children's Healthcare of Atlanta, Atlanta
Ages 16 to 30 · All sexes · Updated Jan 7, 2026 · NCT06374238

Integrative Training Program for Pediatric Sickle Cell Pain

Recruiting
  • Children's Healthcare of Atlanta, Atlanta
  • Arthur M. Blank Hospital | Children's Healthcare of Atlanta, Atlanta
Ages 12 to 18 · All sexes · Updated Nov 14, 2025 · NCT06691867

About Sickle Cell Disease

Sickle cell disease is a group of inherited disorders that affect your red blood cells. It can cause pain, anemia, and other problems. Learn about treatments.

More about Sickle Cell Disease on MedlinePlus

Sickle Cell Disease trials in other cities

Other studies in Atlanta

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.