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Acute Myeloid Leukemia clinical trials in Houston, TX

85 studies for Acute Myeloid Leukemia are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • UT MD Anderson Cancer Center, Houston
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

RecruitingObservational study
  • Texas Children's Hospital, Houston
Ages 0 to 38 · All sexes · Updated Oct 1, 2026 · NCT06131801

A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

RecruitingPhase 1
  • University of Texas MD Anderson Cancer Center, Houston
Ages 12 to 78 · All sexes · Updated Sep 29, 2026 · NCT03802695

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
  • Ben Taub General Hospital, Houston
Ages 18 to 59 · All sexes · Updated Sep 28, 2026 · NCT05554393

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

RecruitingPhase 3
  • Houston Methodist Cancer Center, Houston
  • MD Anderson Cancer Center, Houston
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06852222

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

RecruitingPhase 2
  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
  • Ben Taub General Hospital, Houston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05564390

Liposome-encapsulated Daunorubicin-Cytarabine and Venetoclax in Treating Participants With Relapsed, Refractory or Untreated Acute Myeloid Leukemia

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT03629171

A Phase 1B/2A Trial of NADUNOLIMAB in Combination With Azacitidine (With/Without Venetoclax) in Patients With Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML)

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06548230

Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation

RecruitingPhase 3
  • Clinical Trial Site, Houston
Ages 12 and older · All sexes · Updated Sep 25, 2026 · NCT07211958

Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

RecruitingPhase 1/2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT03661307

A Phase I-II Study Investigating the All-Oral Combination of the Menin Inhibitor SNDX-5613 With Decitabine/Cedazuridine (ASTX727) and Venetoclax in Acute Myeloid Leukemia (SAVE)

RecruitingPhase 1/2Healthy volunteers welcome
  • M D Anderson Cancer Center, Houston
Ages 12 and older · All sexes · Updated Sep 23, 2026 · NCT05360160

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
  • Ben Taub General Hospital, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06317649

Dose Escalation and Expansion of Ziftomenib in Combination With Quizartinib in Acute Myeloid Leukemia

RecruitingPhase 1
  • The University of Texas M. D. Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06769490

Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia

RecruitingPhase 1/2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT03214562

A Multi-Site Break Through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenib

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 12 and older · All sexes · Updated Sep 18, 2026 · NCT06284486

Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy

RecruitingPhase 1
  • M D Anderson Cancer Center, Houston
Ages 1 and older · All sexes · Updated Sep 18, 2026 · NCT03630991

Clinical Study of Anti-FLT3 CAR-T Cells for the Treatment of Relapsed/Refractory AML

RecruitingPhase 1
  • MD Anderson, Houston
Ages 12 and older · All sexes · Updated Sep 17, 2026 · NCT06786533

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

RecruitingPhase 3
  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
  • UT MD Anderson Cancer Center, Houston
6 Months – 21 Years · All sexes · Updated Sep 17, 2026 · NCT04293562

Chimeric Antigen Receptor Treatment Targeting CD70 (SEVENTY)

RecruitingPhase 1
  • Texas Children's Hospital, Houston
  • The Methodist Hospital, Houston
Up to age 75 · All sexes · Updated Sep 16, 2026 · NCT06345027

Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

RecruitingPhase 2
  • The Methodist Hospital Research Institute, Houston
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06824168

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

RecruitingPhase 2
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04996875

Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies

RecruitingPhase 1/2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT03471260

Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT03683433

A Study of BGB-11417 in Participants With Myeloid Malignancies

RecruitingPhase 1/2
  • Md Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT04771130

A Phase Ib Study of Rezatapopt in Combination With Azacitidine in Patients With TP53Y220C Mutant Myeloid Malignancies (Acute Myeloid Leukemia or Myelodysplastic Syndrome)

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06616636

A Study to Assess the Safety, Tolerability, and Antileukemic Activity of Debio 1562M in Participants With Acute Myeloid Leukemia (AML)

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06969430

ASTX727, Venetoclax, and Gilteritinib for the Treatment of Newly Diagnosed, Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

RecruitingPhase 1/2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT05010122

Azacitidine and Enasidenib in Treating Patients With IDH2-Mutant Myelodysplastic Syndrome

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
Ages 12 and older · All sexes · Updated Sep 4, 2026 · NCT03383575

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

RecruitingPhase 1/2
  • MD Anderson, Houston
Ages 12 and older · All sexes · Updated Sep 3, 2026 · NCT04588922

CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), and Myelofibrosis (MF)

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 to 85 · All sexes · Updated Aug 26, 2026 · NCT06834282

CPX-351 and Ivosidenib for the Treatment of IDH1 Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT04493164

Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06533761

Monitoring, Detoxifying, and Rebalancing Metals During Acute Myeloid Leukemia (AML) Therapy, a Phase 2 Randomized Study

RecruitingPhase 2
  • The University of Texas M. D. Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06811233

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

RecruitingPhase 1/2
  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
  • UT MD Anderson Cancer Center, Houston
Up to age 22 · All sexes · Updated Aug 25, 2026 · NCT04726241

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

RecruitingPhase 3
  • Texas Children's Hospital, Houston
29 Days – 21 Years · All sexes · Updated Aug 24, 2026 · NCT05183035

UPDATE AML: UPdated Disease Monitoring And Treatment for Enhanced Outcomes for Pediatric AML

RecruitingEarly phase 1
  • Texas Children's Cancer and Hematology Center, Houston
1 Month – 30 Years · All sexes · Updated Aug 24, 2026 · NCT07059975

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

RecruitingPhase 3
  • University of Texas, Houston
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT07007312

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT06001788

Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS

RecruitingPhase 2/3Healthy volunteers welcome
  • M D Anderson Cancer Center, Houston
Ages 18 to 70 · All sexes · Updated Aug 11, 2026 · NCT04708054

Phase I Study of HC-7366 for Acute Myeloid Leukemia

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT06285890

Personalized NK Cell Therapy in CBT

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
Ages 15 to 80 · All sexes · Updated Jul 30, 2026 · NCT02727803

Decitabine Alone or in Combination With Venetoclax, Gilteritinib, Enasidenib, or Ivosidenib as Maintenance Therapy for the Treatment of Acute Myeloid Leukemia in Remission

RecruitingPhase 1
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT05010772

Cladribine Plus Low Dose Cytarabine (LDAC) Alternating With Decitabine in Patients With Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS)

RecruitingPhase 2
  • University of Texas MD Anderson Cancer Center, Houston
Ages 60 and older · All sexes · Updated Jul 16, 2026 · NCT01515527

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

RecruitingObservational study
  • M.D. Anderson Cancer Center, Houston
  • Texas Children's Hospital - Baylor Medical Center, Houston
All ages · All sexes · Updated Jul 6, 2026 · NCT01351545

A Study of Revumenib and Mezigdomide in People With Leukemia

RecruitingPhase 1/2
  • MD Anderson Cancer Center (Data Collection Only), Houston
Ages 12 and older · All sexes · Updated Jun 22, 2026 · NCT07356154

BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT05768932

Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT02074839

A Phase I Study Investigating the Combination of the Menin Inhibitor Ziftomenib With Venetoclax and Gemtuzumab in Pediatric Patients With Acute Myeloid Leukemia

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 3 to 21 · All sexes · Updated Jun 12, 2026 · NCT06448013

Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

RecruitingPhase 1/2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT04047641

A Phase Ib Trial of Azacitidine, Venetoclax and Allogeneic NK Cells for Acute Myeloid Leukemia (ADVENT-AML)

RecruitingPhase 1
  • M.D. Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT05834244

Venetoclax, Cladribine, Low Dose Cytarabine, and Azacitidine in Treating Patients With Previously Untreated Acute Myeloid Leukemia

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
Ages 50 and older · All sexes · Updated Jun 8, 2026 · NCT03586609

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairment

RecruitingPhase 1
  • MD Anderson, Houston
Ages 18 and older · All sexes · Updated May 28, 2026 · NCT04953897

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment

RecruitingPhase 1
  • MD Anderson, Houston
Ages 18 and older · All sexes · Updated May 28, 2026 · NCT04953910

Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
Ages 12 and older · All sexes · Updated May 22, 2026 · NCT03589729

Decitabine/Cedazuridine and Venetoclax in Combination With Ivosidenib or Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

RecruitingPhase 1/2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated May 20, 2026 · NCT04774393

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 13 and older · All sexes · Updated May 5, 2026 · NCT04771572

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

RecruitingPhase 2/3
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT04256317

PET/MRI, 18F-FDG PET/CT and Whole Body MRI in Finding Extramedullary Myeloid Leukemia in Patients With Newly Diagnosed Acute Myeloid Leukemia

RecruitingPhase 1
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Apr 17, 2026 · NCT02390635

A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

RecruitingPhase 1/2
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT05732103

Safety and Proof-of-Concept Study of RPT1G in Adults With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndromes

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Mar 25, 2026 · NCT07107126

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

RecruitingPhase 1/2
  • MDACC, Houston
Ages 12 and older · All sexes · Updated Mar 24, 2026 · NCT04988555

A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 12 and older · All sexes · Updated Mar 16, 2026 · NCT06994676

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Mar 13, 2026 · NCT05735184

A Phase 1 Study of STX-0712 in Patients With Advanced Hematological Malignancies (CMML and AML)

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Feb 9, 2026 · NCT06950034

CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

RecruitingPhase 1
  • MD Anderson, Houston
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT05143996

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Dec 10, 2025 · NCT06680752

Danvatirsen Monotherapy Followed by Combination With Venetoclax in Relapsed/Refractory MDS & AML

RecruitingPhase 1Healthy volunteers welcome
  • M.D. Anderson Cancer Center, Department of Leukemia, Houston
Ages 18 and older · All sexes · Updated Nov 10, 2025 · NCT05986240

Study of NMS-03597812 in Adult Patients With Relapsed/Refractory Acute Myeloid Leukemia

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Oct 31, 2025 · NCT06549790

AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Oct 2, 2025 · NCT05211570

A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

RecruitingPhase 1
  • The University of Texas M.D. Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT06501196

APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AML

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated May 11, 2025 · NCT06634394

Study of REM-422 in Patients With AML or Higher Risk MDS

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Apr 23, 2025 · NCT06297941

Study of Oral PCLX-001 in R/R Acute Myeloid Leukemia

RecruitingPhase 1
  • MD Anderson Cancer Centre, Houston
Ages 18 and older · All sexes · Updated Mar 10, 2025 · NCT06613217

A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML)

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Mar 10, 2025 · NCT05190471

Clinical Trial of BP1001 in Combination With With Venetoclax Plus Decitabine in AML

RecruitingPhase 2
  • University of Texas M.D. Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Mar 7, 2025 · NCT02781883

Study of VIP943 in Subjects With Advanced CD123+ Hematologic Malignancies

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Nov 15, 2024 · NCT06034275

A Study of BTX-A51 in People With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Mar 20, 2024 · NCT04243785

About Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML) is a cancer of the white blood cells. AML usually gets worse quickly if it is not treated. Read more.

More about Acute Myeloid Leukemia on MedlinePlus

Acute Myeloid Leukemia trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.