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Overweight clinical trials in Philadelphia, PA

14 studies for Overweight are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

RecruitingPhase 3
  • Clinical Renal Associates Ltd., Media · 12 mi away
  • Suburban Research Associates, West Chester · 24 mi away
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07794579

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

RecruitingPhase 3
  • Thomas Jefferson University - Medicine/GI and Hepatology, Philadelphia
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

RecruitingPhase 3
  • Thomas Jefferson University - Medicine/GI and Hepatology, Philadelphia
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

RecruitingPhase 3
  • Abington Medical Specialists, Horsham · 16 mi away
  • Family Practice Associates, Wilmington · 25 mi away
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

RecruitingPhase 3
  • Keystone Clinical Studies, Plymouth Meeting · 12 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07353931

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

RecruitingPhase 3
  • AURORA-1 Clinical Site, Philadelphia
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743463

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

RecruitingPhase 3
  • AURORA-2 Clinical Site, Philadelphia
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

RecruitingPhase 3
  • Suburban Research Associates - West Chester Office, West Chester · 24 mi away
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351045

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, Philadelphia
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight

RecruitingPhase 3
  • UPA Ctr Weight and Eating Dis, Philadelphia
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07770841

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

RecruitingPhase 4
  • Dermatology Associates of Plymouth Meeting, Plymouth Meeting · 12 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06857942

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

RecruitingPhase 3
  • Research Site, Philadelphia
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07784725

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

RecruitingPhase 3
  • ACCOMPLISH-1 Research Site, Philadelphia
Ages 18 to 79 · All sexes · Updated Aug 10, 2026 · NCT07654361

An Acceptance-Based Healthy Lifestyle Intervention for Diverse Adolescents

RecruitingHealthy volunteers welcome
  • Drexel University, Philadelphia
Ages 14 to 19 · Women · Updated Jul 20, 2026 · NCT06147973

Overweight trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.