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Heart Failure clinical trials in Portland, OR

17 studies for Heart Failure are looking for participants at sites in and around Portland (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

RecruitingPhase 3
  • Research Site, Portland
Ages 18 to 130 · All sexes · Updated Oct 2, 2026 · NCT06307652

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

RecruitingPhase 3
  • Oregon Health and Science University, Portland
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT06736574

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • Oregon Health & Science University, Portland
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF

RecruitingPhase 2
  • Oregon Health and Science University, Portland
Ages 40 to 85 · All sexes · Updated Aug 27, 2026 · NCT06793371

Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM

RecruitingObservational study
  • Research Site, Portland
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07690436

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

RecruitingPhase 3
  • Oregon Health & Science University, Portland
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)

Recruiting
  • VA Portland Health Care System, Portland, OR, Portland
Ages 60 and older · All sexes · Updated Aug 14, 2026 · NCT05996328

Assessment of CCM in HF With Higher Ejection Fraction

Recruiting
  • Providence Heart & Vascular, Portland
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05064709

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • Providence St. Vincent's - Portland, Portland
  • Oregon Health Science Portland, Portland
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • Oregon Health & Science University, Portland
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

CCM OPEN HF Registry

RecruitingObservational study
  • Providence St. Vincent Medical Center, Portland
  • Legacy Medical Group Cardiology, Portland
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT07112924

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • Oregon Health & Science University (OHSU), Portland
  • Providence Heart Institute, Portland
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

RecruitingPhase 3
  • Oregon Health and Science University, Portland
Ages 18 to 75 · All sexes · Updated Mar 24, 2026 · NCT06217302

Left vs Left Randomized Clinical Trial

Recruiting
  • Oregon Health & Science University, Portland
Ages 18 and older · All sexes · Updated Oct 2, 2025 · NCT05650658

Cardiogenic Shock Working Group Registry

RecruitingObservational study
  • Providence St. Vincent Heart Clinic, Portland
Ages 18 and older · All sexes · Updated Jun 6, 2025 · NCT04682483

Rural Community Peer Partnerships for Improving Methamphetamine-Associated Heart Failure Screening and Engagement

Recruiting
  • Oregon Health & Science University, Portland
Ages 18 and older · All sexes · Updated Mar 21, 2025 · NCT06461962

HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry

RecruitingObservational study
  • Providence Heart Institute, Portland
Ages 18 to 100 · All sexes · Updated May 22, 2024 · NCT06425848

About Heart Failure

Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.

More about Heart Failure on MedlinePlus

Heart Failure trials in other cities

Other studies in Portland

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.