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Sickle Cell Disease clinical trials in Baltimore, MD

7 studies for Sickle Cell Disease are looking for participants at sites in and around Baltimore (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

RecruitingPhase 3
  • The Johns Hopkins University School of Medicine, Baltimore
Ages 12 to 100 · All sexes · Updated Sep 28, 2026 · NCT06439082

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

RecruitingPhase 1/2Healthy volunteers welcome
  • Local Institution - 0064, Baltimore
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06481306

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

RecruitingObservational study
  • Johns Hopkins University Hemophilia Treatment Center, Baltimore
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628

Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

RecruitingPhase 2
  • University of Maryland, Baltimore
Ages 12 and older · All sexes · Updated Aug 14, 2026 · NCT06699849

The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease

RecruitingPhase 3
  • University of Maryland School of Medicine - Baltimore- Site Number : 8400041, Baltimore
Ages 10 to 65 · All sexes · Updated Jul 29, 2026 · NCT06975865

Cooperative Assessment of Late Effects for SCD Curative Therapies

RecruitingObservational study
  • Johns Hopkins Hospital, Baltimore
Ages 4 to 65 · All sexes · Updated Jul 27, 2026 · NCT05153967

Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises

Recruiting
  • University of Maryland Medical Systems, Baltimore
Ages 18 and older · All sexes · Updated Dec 24, 2025 · NCT06184126

About Sickle Cell Disease

Sickle cell disease is a group of inherited disorders that affect your red blood cells. It can cause pain, anemia, and other problems. Learn about treatments.

More about Sickle Cell Disease on MedlinePlus

Sickle Cell Disease trials in other cities

Other studies in Baltimore

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.