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Heart Diseases clinical trials in Philadelphia, PA

11 studies for Heart Diseases are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

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ELEVATE-HFpEF Clinical Study

Recruiting
  • Lankenau Institute for Medical Research, Wynnewood · 7 mi away
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
  • Lankenau Medical Center, Wynnewood · 7 mi away
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • Thomas Jefferson University Hospital, Philadelphia
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

Recruiting
  • Hospital of the University of Pennsylvania, Philadelphia
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489

Abbott Structural Heart Device Registry

RecruitingObservational study
  • University of Pennsylvania, Philadelphia
All ages · All sexes · Updated Sep 1, 2026 · NCT06590467

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

RecruitingPhase 3
  • Penn Presbyterian Medical Center, Philadelphia
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure

Recruiting
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT06552637

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • University of Pennsylvania, Philadelphia
  • Abington Memorial Hospital, Abington · 12 mi away
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • University of Pennsylvania, Philadelphia
  • Lankenau Institute of Medical Research, Wynnewood · 7 mi away
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

Recruiting
  • University of Pennsylvania, Philadelphia
  • Lankenau Medical Center, Wynnewood · 7 mi away
Ages 18 and older · Women · Updated Apr 1, 2026 · NCT04124120

PARTNER 3 Trial - Aortic Valve-in-Valve

Recruiting
  • University of Pennsylvania Hospital, Philadelphia
  • Lankenau Medical Center, Wynnewood · 7 mi away
All ages · All sexes · Updated May 10, 2024 · NCT03003299

About Heart Diseases

Heart disease is the leading cause of death in the U.S. Learn about the different types of heart diseases, and what you can do to try to prevent them.

More about Heart Diseases on MedlinePlus

Heart Diseases trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.