Home โบ Lung Cancer
Lung Cancer clinical trials recruiting in the U.S.
348 studies for Lung Cancer are recruiting participants at sites across the United States.
Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.
Cities with the most studies
- Houston, TX78 studies
- Boston, MA62 studies
- New York City, NY60 studies
- Los Angeles, CA45 studies
- Arlington, VA41 studies
- Washington, DC41 studies
- Chicago, IL41 studies
- Nashville, TN40 studies
- Baltimore, MD40 studies
- St. Louis, MO39 studies
- Columbus, OH37 studies
- Philadelphia, PA36 studies
- Seattle, WA33 studies
- Durham, NC32 studies
- Atlanta, GA29 studies
- Tampa, FL29 studies
- Dallas, TX27 studies
- San Antonio, TX26 studies
- Cleveland, OH26 studies
- Portland, OR26 studies
- Baldwin Park, CA24 studies
- San Francisco, CA23 studies
- San Diego, CA23 studies
- Pittsburgh, PA23 studies
- Ann Arbor, MI23 studies
- Edison, NJ23 studies
- New Haven, CT22 studies
- Sacramento, CA22 studies
- Queens, NY22 studies
- Milwaukee, WI21 studies
- Salt Lake City, UT21 studies
- Orlando, FL21 studies
- Minneapolis, MN20 studies
- Detroit, MI20 studies
- Rochester, MN20 studies
- Miami, FL20 studies
- Aurora, CO19 studies
- Evanston, IL19 studies
- Oklahoma City, OK19 studies
- Kansas City, MO19 studies
By state
- Alabama16 studies
- Alaska7 studies
- Arizona34 studies
- Arkansas19 studies
- California112 studies
- Colorado38 studies
- Connecticut30 studies
- Delaware11 studies
- District of Columbia27 studies
- Florida76 studies
- Georgia40 studies
- Hawaii8 studies
- Idaho11 studies
- Illinois62 studies
- Indiana25 studies
- Iowa19 studies
- Kansas21 studies
- Kentucky26 studies
- Louisiana16 studies
- Maine12 studies
- Maryland56 studies
- Massachusetts75 studies
- Michigan44 studies
- Minnesota42 studies
- Mississippi14 studies
- Missouri44 studies
- Montana14 studies
- Nebraska19 studies
- Nevada11 studies
- New Hampshire12 studies
- New Jersey42 studies
- New Mexico15 studies
- New York93 studies
- North Carolina50 studies
- North Dakota15 studies
- Ohio68 studies
- Oklahoma20 studies
- Oregon31 studies
- Pennsylvania57 studies
- Rhode Island6 studies
- South Carolina19 studies
- South Dakota15 studies
- Tennessee58 studies
- Texas101 studies
- Utah25 studies
- Vermont7 studies
- Virginia58 studies
- Washington43 studies
- West Virginia11 studies
- Wisconsin31 studies
Recently updated studies
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Oct 2, 2026 ยท NCT04267848Evaluation for NCI Surgery Branch Clinical Research Protocols
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Oct 2, 2026 ยท NCT00001823Prospective Multiomic Analysis in Small-Cell Lung Cancer
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Oct 2, 2026 ยท NCT07795411Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining
RecruitingObservational study
Ages 2 to 120 ยท All sexes ยท Updated Oct 2, 2026 ยท NCT00242723Adding Certolizumab to Chemotherapy + Nivolumab in People Who Have Lung Cancer That Can Be Treated With Surgery
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Oct 2, 2026 ยท NCT04991025Smoking Cessation CM for Veterans With or at Risk for Cancer
RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Oct 2, 2026 ยท NCT06432985The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
RecruitingPhase 1/2
Ages 12 and older ยท All sexes ยท Updated Oct 2, 2026 ยท NCT04585750Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma
RecruitingObservational study
Ages 2 to 100 ยท All sexes ยท Updated Oct 2, 2026 ยท NCT01950572Distance-Based Exercise to Preserve Function and Prevent Disability
Recruiting
Ages 18 and older ยท All sexes ยท Updated Oct 2, 2026 ยท NCT07059884Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma
RecruitingPhase 1
Ages 18 to 120 ยท All sexes ยท Updated Oct 2, 2026 ยท NCT06885697Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01I/KEYMAKER-U01I)
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Oct 2, 2026 ยท NCT06780098Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 ยท All sexes ยท Updated Oct 2, 2026 ยท NCT05334069Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis
RecruitingObservational study
Ages 3 and older ยท All sexes ยท Updated Oct 2, 2026 ยท NCT01441089Cemiplimab and Fianlimab Before Surgery for the Treatment of Stage IB-IIIB Non-Small Cell Lung Cancer
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Oct 1, 2026 ยท NCT06918132A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F)
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Oct 1, 2026 ยท NCT07286149A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Oct 1, 2026 ยท NCT06172478Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
RecruitingPhase 3
Ages 70 and older ยท All sexes ยท Updated Oct 1, 2026 ยท NCT06096844Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Oct 1, 2026 ยท NCT04181060Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Oct 1, 2026 ยท NCT06625775Empathic Communication Skills (ECS) Training
RecruitingHealthy volunteers welcome
Ages 18 to 100 ยท All sexes ยท Updated Oct 1, 2026 ยท NCT05456841Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Oct 1, 2026 ยท NCT06498635The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 30, 2026 ยท NCT07285044Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 30, 2026 ยท NCT06765109Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 29, 2026 ยท NCT06881784DK222 Study at Hopkins
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Sep 29, 2026 ยท NCT07140315From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.