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Prostate Cancer clinical trials in Omaha, NE

27 studies for Prostate Cancer are looking for participants at sites in and around Omaha (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome

Alegent Health Immanuel Medical Center, Omaha
Alegent Health Bergan Mercy Medical Center, Omaha
Alegent Health Lakeside Hospital, Omaha

Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2

Nebraska Medicine-Village Pointe, Omaha
University of Nebraska Medical Center, Omaha
Nebraska Medicine-Bellevue, Bellevue · 9 mi away

Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

RecruitingPhase 1/2

Urology Cancer Center, PC, Omaha

Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06800313

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

RecruitingPhase 3

Oncology Hematology West P.C. dba Nebraska Cancer Specialists ( Site 0026), Omaha

Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

RecruitingPhase 2/3

Nebraska Cancer Specialists, Omaha

Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06780670

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

RecruitingPhase 3

Nebraska Cancer Specialists, Omaha

Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06855277

PSMA-PET Guided De-escalation of Salvage Radiation Treatment in Recurrent Prostate Cancer

RecruitingPhase 2

University of Nebraska Medical Center, Omaha

Ages 30 and older · Men · Updated Sep 21, 2026 · NCT07234981

A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1

XCancer, Omaha

Ages 18 and older · Men · Updated Sep 15, 2026 · NCT07581184

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

RecruitingPhase 3

XCancer Omaha LLC, Omaha

Ages 18 and older · Men · Updated Sep 11, 2026 · NCT06056830

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

RecruitingPhase 3

Nebraska Medicine-Village Pointe, Omaha
University of Nebraska Medical Center, Omaha
Nebraska Medicine-Bellevue, Bellevue · 9 mi away

Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

RecruitingPhase 1/2

Research Site, Omaha

Ages 18 to 99 · Men · Updated Aug 27, 2026 · NCT07590934

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

RecruitingPhase 3

Research Site, Omaha

Ages 18 and older · Men · Updated Aug 26, 2026 · NCT07611110

Study of Oral MRT-2359 With Apalutamide in Prostate Cancer

RecruitingPhase 2

XCancer Omaha, Omaha

Ages 18 and older · Men · Updated Aug 24, 2026 · NCT07745361

A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

RecruitingPhase 1/2

Nebraska Cancer Specialists, Omaha

Ages 18 and older · Men · Updated Aug 20, 2026 · NCT06785636

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

RecruitingPhase 3

Alegent Health Bergan Mercy Medical Center, Omaha

Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

Abi/Pred + ADT vs ADT in PSMA-Positive, Conventionally Node-Negative Prostate Cancer

RecruitingPhase 2

University of Nebraska Medical Center, Omaha

Ages 30 and older · Men · Updated Aug 19, 2026 · NCT07237269

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

RecruitingPhase 3

Alegent Health Immanuel Medical Center, Omaha
Alegent Health Bergan Mercy Medical Center, Omaha
Alegent Health Lakeside Hospital, Omaha

Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Integrated Cancer Repository for Cancer Research

RecruitingObservational studyHealthy volunteers welcome

Methodist Estabrook Cancer Center, Omaha
Nebraska Methodist Health System, Omaha
University of Nebraska Medical Center, Omaha
and 1 more

Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

RecruitingPhase 1

Nebraska Cancer Specialists (Midwest Cancer Center - Legacy), Omaha
XCancer Omaha / Urology Cancer Center, Omaha

Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05283330

Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

RecruitingPhase 4

Urology Cancer Center PC, Omaha
Nebraska Cancer Specialists, Omaha

Ages 18 to 100 · Men · Updated Jun 4, 2026 · NCT05803941

Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection

RecruitingPhase 1/2

XCancer Omaha / Urology Cancer Center, Omaha

Ages 18 and older · Men · Updated May 14, 2026 · NCT05413850

A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1

Research Site, Omaha

Ages 18 and older · Men · Updated May 12, 2026 · NCT06879041

Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

RecruitingPhase 2

Alegent Health Immanuel Medical Center, Omaha
Alegent Health Bergan Mercy Medical Center, Omaha
Alegent Health Lakeside Hospital, Omaha
and 3 more

Ages 18 and older · Men · Updated Jan 29, 2026 · NCT05806515

Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

RecruitingPhase 3

Nebraska Medicine-Village Pointe, Omaha
University of Nebraska Medical Center, Omaha
Nebraska Medicine-Bellevue, Bellevue · 9 mi away

Ages 18 and older · Men · Updated Jan 22, 2026 · NCT06470243

High-dose Brachytherapy Boost With Stereostatic Body Radiation Therapy to Intermediate or Higher Risk Prostate Cancer

Recruiting

University of Nebraska Medical Center, Omaha

Ages 19 and older · Men · Updated Nov 5, 2025 · NCT05754580

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study

Massive Bio SYNERGY-AI site, Omaha

All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

RecruitingPhase 3

Nebraska Methodist Hospital, Omaha
Nebraska Medicine-Village Pointe, Omaha
University of Nebraska Medical Center, Omaha
and 1 more

Ages 18 and older · Men · Updated Sep 11, 2025 · NCT03678025

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Omaha

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.