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Sickle Cell Disease clinical trials in Pittsburgh, PA

9 studies for Sickle Cell Disease are looking for participants at sites in and around Pittsburgh (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)

RecruitingPhase 1
  • University of Pittsburgh Medical Center (UPMC), Pittsburgh
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07187973

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

RecruitingPhase 1/2Healthy volunteers welcome
  • Local Institution - 0032, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06481306

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

RecruitingObservational study
  • Hemophilia Center of Western Pennsylvania, Pittsburgh
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628

Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

RecruitingPhase 2
  • University of Pittsburgh, Pittsburgh
  • Hillman Cancer Center, Pittsburgh
Ages 12 and older · All sexes · Updated Aug 14, 2026 · NCT06699849

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

RecruitingPhase 1/2
  • Children's Hospital of Pittsburgh of UPMC, Pittsburgh
Ages 5 to 40 · All sexes · Updated Aug 13, 2026 · NCT03653338

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

RecruitingObservational study
  • UPMC Children's Hospital of Pittsburgh, Pittsburgh
2 Months – 60 Years · All sexes · Updated Jan 13, 2026 · NCT04528355

Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain

Recruiting
  • UPMC University of Pittsburgh Classical Hematology Adult Clinic, Pittsburgh
  • UPMC Children's Hospital of Pittsburgh, Pittsburgh
Ages 16 to 30 · All sexes · Updated Jan 7, 2026 · NCT06374238

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

RecruitingPhase 2
  • UPMC Children's Hospital of Pittsburgh, Pittsburgh
2 Months – 55 Years · All sexes · Updated Dec 15, 2025 · NCT01962415

Cutaneous Hydration Assessment in SCD

Recruiting
  • UPMC Sickle Cell Clinic, Pittsburgh
Ages 12 and older · All sexes · Updated Nov 12, 2025 · NCT05210114

About Sickle Cell Disease

Sickle cell disease is a group of inherited disorders that affect your red blood cells. It can cause pain, anemia, and other problems. Learn about treatments.

More about Sickle Cell Disease on MedlinePlus

Sickle Cell Disease trials in other cities

Other studies in Pittsburgh

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.