🔎 Trials Near Me

Home › Brain Tumors › North Carolina › Durham

Brain Tumors clinical trials in Durham, NC

14 studies for Brain Tumors are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • Duke University School of Medicine, Durham
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

RecruitingPhase 2
  • Local Institution - 0100, Durham
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1
  • Duke Cancer Institute, Durham
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

Targeted Pediatric High-Grade Glioma Therapy

RecruitingObservational study
  • Duke University Health System, Durham
12 Months – 39 Years · All sexes · Updated Sep 8, 2026 · NCT05839379

A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma

RecruitingPhase 2
  • Duke University, Durham
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07428616

Study of Olutasidenib and Temozolomide in HGG

RecruitingPhase 2
  • Duke University Health System, Durham
Ages 12 to 39 · All sexes · Updated Sep 1, 2026 · NCT06161974

ViCToRy: Vorasidenib in Combination With Tumor Specific Peptide Vaccine for Recurrent IDH1 Mutant Lower Grade Gliomas

RecruitingPhase 1
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT05609994

MRI Biomarkers for Radiation-Induced Neurocognitive Decline Following SRS of Newly Diagnosed Brain Mets

RecruitingObservational study
  • University of North Carolina at Chapel Hill, Department of Radiation Oncology, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT04073966

B6 Administration for Levetiracetam-Associated Neurobehavioral Changes and Epilepsy

Recruiting
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT07271966

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

RecruitingPhase 2
  • Duke University Health System, Durham
12 Months – 39 Years · All sexes · Updated May 29, 2026 · NCT05843253

Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc

RecruitingPhase 1
  • Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT05366179

Key Longitudinal Associations With Risk and Glioblastoma Outcomes

RecruitingObservational study
  • Duke University, Durham
Ages 18 and older · All sexes · Updated Jan 20, 2026 · NCT06625684

Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors

RecruitingObservational study
  • Duke Cancer Center, Durham
Ages 18 and older · All sexes · Updated Nov 19, 2025 · NCT05480644

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

RecruitingPhase 2
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Jun 27, 2025 · NCT03175224

About Brain Tumors

A brain tumor is a growth of abnormal cells in the brain tissue. Learn the types of tumors, symptoms, how they are diagnosed and treatment options.

More about Brain Tumors on MedlinePlus

Brain Tumors trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.