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Colorectal Cancer clinical trials in St. Louis, MO
50 studies for Colorectal Cancer are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.
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The Vanguard Study: Testing a New Way to Screen for Cancer
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer
RecruitingPhase 2
- Washington University, St Louis
A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors
RecruitingPhase 1
- Washington University Medicine, St Louis
Colonoscopy vs Stool Testing for Older Adults With Colon Polyps
Recruiting
- Washington University School of Medicine, St Louis
Family Communications After Genetic Testing
RecruitingHealthy volunteers welcome
- Mercy Infusion Center - Chippewa, St Louis
- Mercy Hospital South, St Louis
- Missouri Baptist Medical Center, St Louis
- and 4 more
Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial
RecruitingPhase 2
- Mercy Hospital South, St Louis
- Missouri Baptist Medical Center, St Louis
- Mercy Hospital Saint Louis, St Louis
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
RecruitingObservational studyHealthy volunteers welcome
- Mercy Infusion Center - Chippewa, St Louis
- Mercy Hospital South, St Louis
- Missouri Baptist Medical Center, St Louis
- and 4 more
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
RecruitingPhase 1
- Washington University School of Medicine, St Louis
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
RecruitingPhase 3
- Washington University School Of Medicine, St Louis
Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
RecruitingObservational study
- Washington University, St Louis
Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors
RecruitingPhase 1
- Research Site, St Louis
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
RecruitingPhase 3
- Washington University School Of Medicine, St Louis
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
RecruitingPhase 2/3
- Washington University School OF Medicine-Siteman Cancer Center, St Louis
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
RecruitingPhase 1
- Washington University, St Louis
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
RecruitingPhase 1
- Washington University School of Medicine in St. Louis, St Louis
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
RecruitingPhase 1/2
- Washington University, St Louis
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
RecruitingPhase 3
- Washington University School of Medicine, St Louis
Testing for Safety and Colorectal Cancer Preventive Effects of ONC201
RecruitingPhase 1
- Washington University School of Medicine, St Louis
Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal Cancer
RecruitingPhase 1
- Washington University School of Medicine, St Louis
- Siteman Cancer Center-South County, St Louis
- Siteman Cancer Center at Christian Hospital, St Louis
- and 2 more
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
RecruitingPhase 1
- Washington University School of Medicine, St Louis
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
RecruitingPhase 3
- Clinical Study Site, O'Fallon · 16 mi away
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
RecruitingPhase 1/2
- Washington University School of Medicine, St Louis
FOG-001 in Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- Washington University School of Medicine, St Louis
IDOV-Immune for Advanced Solid Tumors
RecruitingPhase 1
- Washington University School of Medicine, St Louis
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- Washington University, St Louis
AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors
RecruitingPhase 1
- Siteman Cancer Center - Washington University, St Louis
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
RecruitingPhase 1/2
- Washington University School of Medicine at St Louis, St Louis
Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors
RecruitingPhase 1
- Investigative Site #110, St Louis
Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)
Recruiting
- Washington University School of Medicine, St Louis
CARE Tool Study Aim 3
Recruiting
- Washington University School of Medicine, St Louis
- Alton Memorial Hospital, Alton · 18 mi away
A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
RecruitingPhase 4
- SSM Health St. Louis DePaul Hospital, St Louis
- Washington University School of Medicine, St Louis
Lead-212 PSV359 Therapy for Patients With Solid Tumors
RecruitingPhase 1/2
- Saint Louis University, St Louis
Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)
RecruitingObservational study
- Mercy Hospital - South, St Louis
- Mercy Hospital -STL, St Louis
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
RecruitingPhase 1/2
- Washington University, St Louis
A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
RecruitingPhase 1
- Research Site, St Louis
KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
RecruitingPhase 1
- Washington University School of Medicine, St Louis
A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
RecruitingPhase 1
- Washington University School of Medicine, St Louis
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
RecruitingPhase 1/2
- Washington University School of Medicine, St Louis
Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors
RecruitingPhase 3Healthy volunteers welcome
- Mercy Infusion Center - Chippewa, St Louis
- Mercy Hospital South, St Louis
- Missouri Baptist Medical Center, St Louis
- and 5 more
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
RecruitingObservational study
- Mercy Hospital South, St Louis
- Missouri Baptist Medical Center, St Louis
- Mercy Hospital Saint Louis, St Louis
- and 4 more
Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- Washington University, St Louis
Ultrasound and Photoacoustic Imaging for Enhanced Differential Diagnosis of Rectal Cancer
Recruiting
- Washington University School of Medicine, St Louis
JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration
RecruitingPhase 1/2
- Washington University, St Louis
LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia
RecruitingObservational study
- Mercy Hospital South, St Louis
- Missouri Baptist Medical Center, St Louis
- BJC Outpatient Center at Sunset Hills, Sunset Hills · 13 mi away
- and 3 more
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
RecruitingObservational study
- Missouri Baptist Medical Center, St Louis
- BJC Outpatient Center at Sunset Hills, Sunset Hills · 13 mi away
- Cancer Care Center of O'Fallon, O'Fallon · 16 mi away
Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
RecruitingPhase 1
- Washington University Medical Campus, St Louis
ColoSense Post-Approval Study
RecruitingObservational studyHealthy volunteers welcome
- Decentralized Study, St Louis
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
RecruitingPhase 1/2
- Washington University, St Louis
ColoCare Study - Colorectal Cancer Cohort
RecruitingObservational study
- Washington University School of Medicine, St Louis
Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays
RecruitingObservational study
- Washington University School of Medicine, St Louis
- Mercy Clinic Oncology and Hematology - Sindelar Cancer Center, St Louis
- Mercy Clinic Oncology and Hematology - David C. Pratt Cancer Center, St Louis
About Colorectal Cancer
Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.
More about Colorectal Cancer on MedlinePlus
Colorectal Cancer trials in other cities
- Houston, TX102 studies
- New York City, NY78 studies
- Nashville, TN69 studies
- Boston, MA63 studies
- Los Angeles, CA59 studies
- Arlington, VA52 studies
- San Antonio, TX46 studies
- Philadelphia, PA44 studies
- Grand Rapids, MI40 studies
- Baldwin Park, CA37 studies
- Chicago, IL34 studies
- Tampa, FL34 studies
Other studies in St. Louis
- Non-Small Cell Lung Cancer73 studies
- Breast Cancer64 studies
- Metastatic Cancer54 studies
- Cancer (all types)46 studies
- Prostate Cancer46 studies
- Lung Cancer39 studies
- Ovarian Cancer38 studies
- Pancreatic Cancer33 studies
- Endometrial Cancer29 studies
- Head and Neck Squamous Cell Carcinoma28 studies
- Heart Failure26 studies
- Obesity25 studies
From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.