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Prostate Cancer clinical trials in Dallas, TX

36 studies for Prostate Cancer are looking for participants at sites in and around Dallas (within about 30 miles). Open a study to see who can join and how to contact the study team.

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • UT Southwest Simmons Cancer Center, Dallas
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

RecruitingPhase 3
  • UT Southwestern Simmons Cancer Center - RedBird, Dallas
  • UT Southwestern/Simmons Cancer Center-Dallas, Dallas
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT06931340

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

RecruitingPhase 2
  • Parkland Memorial Hospital, Dallas
  • UT Southwestern Simmons Cancer Center - RedBird, Dallas
  • UT Southwestern/Simmons Cancer Center-Dallas, Dallas
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06632977

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • UT Southwestern Simmons Cancer Center - RedBird, Dallas
  • UT Southwestern/Simmons Cancer Center-Dallas, Dallas
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

DESTINY-PANTUMOUR04

RecruitingObservational study
  • Research Site, Dallas
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

RecruitingPhase 3
  • Texas Oncology - DFW ( Site 8001), Dallas
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

RecruitingPhase 3
  • University of Texas Southwestern Medical Center - Simmons Cancer Center, Dallas
  • University of Texas Southwestern Medical Center - William P. Clements, Jr., University Hospital, Dallas
  • University of Texas Southwestern Simmons Cancer Center - Redbird, Dallas
  • and 2 more
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07028853

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

RecruitingPhase 1
  • Texas Oncology - DFW (Sammons CC), Dallas
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

RecruitingPhase 3
  • University of Texas Southwestern Medical Center, Dallas
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

RecruitingPhase 3
  • Parkland Health & Hospital System ( Site 0069), Dallas
  • UT Southwestern Medical Center ( Site 0039), Dallas
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

RecruitingPhase 3
  • Urology Clinics of North Texas, Dallas
  • University of Texas Southwestern Medical Center, Dallas
Ages 18 and older · Men · Updated Sep 11, 2026 · NCT06056830

Study of JANX014 in Subjects With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1
  • SCRI at Mary Crowley, Dallas
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07545811

A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-1)

RecruitingPhase 3
  • Urology Clinics Of North Texas, Dallas
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07723248

A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer

RecruitingPhase 2
  • University of Texas Southwestern Medical Center, Dallas
Ages 18 and older · Men · Updated Aug 31, 2026 · NCT05726292

A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

RecruitingPhase 1/2
  • University of Texas Southwestern Medical Center, Dallas
Ages 18 and older · Men · Updated Aug 20, 2026 · NCT06785636

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

RecruitingPhase 3
  • Parkland Memorial Hospital, Dallas
  • UT Southwestern Simmons Cancer Center - RedBird, Dallas
  • UT Southwestern/Simmons Cancer Center-Dallas, Dallas
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

RecruitingPhase 2
  • University of Texas Southwestern Medical Center, Dallas
Ages 18 and older · Men · Updated Aug 17, 2026 · NCT06842498

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

RecruitingPhase 1
  • Mary Crowley Cancer Research, Dallas
  • University of Texas Southwestern Medical Center, Dallas
Ages 18 to 100 · Men · Updated Aug 13, 2026 · NCT05519449

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

RecruitingPhase 3
  • Dallas VA Medical Center, Dallas
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Study of ORIC-944 in Patients With Metastatic Prostate Cancer

RecruitingPhase 1
  • Urology Clinics of North Texas, Dallas
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT05413421

Phase II Trial of PSA Response-based Androgen Deprivation Therapy and Nodal Coverage for Prostate Cancer Early Salvage Radiotherapy (RANGER)

RecruitingPhase 2
  • UT Southwestern Medical Center-Dallas, Dallas
Ages 18 and older · Men · Updated Jun 30, 2026 · NCT07313241

Trial of Curcumin to Prevent Progression of Low-risk Prostate Cancer Under Active Surveillance

RecruitingPhase 3
  • UT Southwestern Medical Center, Dallas
Ages 40 to 89 · Men · Updated Jun 15, 2026 · NCT03769766

Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

RecruitingPhase 4
  • Univ of Texas Southwest Med Center, Dallas
Ages 18 to 100 · Men · Updated Jun 4, 2026 · NCT05803941

Outcomes of Focal Ablation for Prostate Cancer

RecruitingObservational study
  • UTSW, Dallas
Ages 18 to 90 · Men · Updated Apr 17, 2026 · NCT05478694

Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical Prostatectomy

RecruitingPhase 3
  • UT Southwestern Medical Center, Dallas
Ages 30 to 80 · Men · Updated Mar 30, 2026 · NCT02064673

Study of AZD0754 in Participants With Metastatic Prostate Cancer

RecruitingPhase 1/2
  • Research Site, Dallas
Ages 18 to 130 · Men · Updated Feb 23, 2026 · NCT06267729

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • Mary Crowley Cancer Research, Dallas
  • Baylor University Medical Center, Dallas
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

RecruitingPhase 1
  • Urology Clinics of North Texas, Dallas
Ages 18 and older · Men · Updated Feb 4, 2026 · NCT04729114

Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

RecruitingPhase 4
  • UT Southwestern Medical Center, Dallas
Ages 18 to 64 · All sexes · Updated Jan 22, 2026 · NCT04373564

Non-significant Risk (NSR) Study of [68Ga]-PSMA-11 (Illuccix) as a BgRT BioGuide on RefleXion X1

RecruitingObservational study
  • Ut Southwestern Medical Center, Dallas
All ages · Men · Updated Jan 12, 2026 · NCT06353321

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 120, Dallas
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Dallas
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

RecruitingPhase 3
  • Parkland Memorial Hospital, Dallas
  • UT Southwestern Simmons Cancer Center - RedBird, Dallas
  • UT Southwestern/Simmons Cancer Center-Dallas, Dallas
Ages 18 and older · Men · Updated Sep 11, 2025 · NCT03678025

Customized TULSA-PRO Ablation Registry

RecruitingObservational study
  • University of Texas Southwestern Medical Center, Dallas
Ages 18 and older · Men · Updated Nov 6, 2024 · NCT05001477

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Dallas

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.