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Prostate Cancer clinical trials in Rochester, MN

22 studies for Prostate Cancer are looking for participants at sites in and around Rochester (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

RecruitingPhase 3
  • Research Site, Rochester
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06952803

Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial

RecruitingPhase 2
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT07650240

A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate Cancer

RecruitingPhase 1/2
  • GSK Investigational Site, Rochester
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06990880

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

RecruitingPhase 3
  • Mayo Clinic in Rochester, Minnesota-Mayo Clinic Comprehensive Cancer Center ( Site 0078), Rochester
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

Recruiting
  • Mayo Clinic, Rochester
Ages 18 and older · Men · Updated Sep 14, 2026 · NCT06511141

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

RecruitingPhase 3
  • Mayo Clinic- Rochester, Rochester
Ages 18 and older · Men · Updated Sep 11, 2026 · NCT06056830

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

RecruitingPhase 1
  • Mayo Clinic, Rochester
Ages 18 to 100 · Men · Updated Aug 13, 2026 · NCT05519449

Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate Cancer

Recruiting
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · Men · Updated Jul 30, 2026 · NCT06325046

MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Low to Intermediate Grade Prostate Cancer

Recruiting
  • Mayo Clinic in Rochester, Rochester
Ages 45 to 80 · Men · Updated Jul 22, 2026 · NCT05438563

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

RecruitingPhase 1
  • Mayo Clinic, Rochester
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT07103018

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

RecruitingHealthy volunteers welcome
  • Mayo Clinic in Rochester, Rochester
Ages 18 to 85 · All sexes · Updated Jun 10, 2026 · NCT06788886

Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

RecruitingPhase 4
  • Mayo Clinic Rochester, Rochester
Ages 18 to 100 · Men · Updated Jun 4, 2026 · NCT05803941

A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1
  • Research Site, Rochester
Ages 18 and older · Men · Updated May 12, 2026 · NCT06879041

Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion and Non-Contrast MRI

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Apr 17, 2026 · NCT06315595

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT06395519

Screening and Staging of Benign vs Malignant Pelvic Abnormalities

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT07407959

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic, Rochester
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

Understanding of Genetics by Men at Risk for Prostate Cancer

RecruitingHealthy volunteers welcome
  • Mayo Clinic, Rochester
Ages 40 to 95 · Men · Updated Nov 6, 2025 · NCT04550845

A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #14, Rochester
Ages 18 and older · All sexes · Updated Sep 5, 2025 · NCT05932862

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Rochester

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.