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Cardiovascular Disease clinical trials in Cleveland, OH

22 studies for Cardiovascular Disease are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Product Surveillance Registry

RecruitingObservational study
  • Cleveland, Cleveland
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Zenith® Fenestrated+ Clinical Study

Recruiting
  • Cleveland Clinic Foundation, Cleveland
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
  • University Hospitals Cleveland Medical Center, Cleveland
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • Cleveland Clinic, Cleveland
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

RecruitingPhase 3
  • Cleveland Clinic Foundation, Cleveland
Ages 18 to 100 · All sexes · Updated Sep 4, 2026 · NCT07517263

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

Recruiting
  • Cleveland Clinic Foundation, Cleveland
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • Case Western Reserve University, Cleveland
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

The Oxford Risk Factors And Non-Invasive Imaging Study

RecruitingObservational study
  • Cleveland Clinic, Cleveland
Ages 18 to 99 · All sexes · Updated Jul 31, 2026 · NCT05169333

Longitudinal Validation of CIRC Technologies

RecruitingObservational studyHealthy volunteers welcome
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07081711

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • University Hospital (Cleveland), Cleveland
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Cardiovascular and Metabolic Sciences Biorepository

RecruitingObservational studyHealthy volunteers welcome
  • Cleveland Clinic Main Campus, Cleveland
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06560424

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • The Cleveland Clinic Foundation, Cleveland
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

CV Imaging of Metabolic Interventions

RecruitingObservational studyHealthy volunteers welcome
  • Cardiovascular Innovation Research Center, Cleveland
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT05650307

Development of CIRC Technologies

RecruitingObservational studyHealthy volunteers welcome
  • Cardiovascular Innovation Research Center, Cleveland
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT05654272

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

RecruitingPhase 3
  • Cleveland Clinic Foundation, Cleveland
Ages 18 to 75 · All sexes · Updated Mar 24, 2026 · NCT06217302

Vascular Lab Resource (VLR) Biorepository

RecruitingObservational study
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Dec 19, 2025 · NCT05628948

MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels

Recruiting
  • University Hospitals, Cleveland Medical Center, Cleveland
  • Cleveland Clinic, Cleveland
Ages 18 to 80 · All sexes · Updated Sep 11, 2025 · NCT06271590

MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

Recruiting
  • Cleveland Clinic, Cleveland
Ages 18 to 110 · All sexes · Updated Feb 25, 2025 · NCT05908331

PARTNER 3 Trial - Aortic Valve-in-Valve

Recruiting
  • The Cleveland Clinic Foundation, Cleveland
All ages · All sexes · Updated May 10, 2024 · NCT03003299

Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY "SYMPHONY-HF"

Recruiting
  • Cleveland Clinic, Cleveland
Ages 40 and older · All sexes · Updated Aug 4, 2023 · NCT05919342

Cardiovascular Disease trials in other cities

Other studies in Cleveland

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.