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Depression clinical trials in Portland, OR

6 studies for Depression are looking for participants at sites in and around Portland (within about 30 miles). Open a study to see who can join and how to contact the study team.

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

RecruitingPhase 3
  • VA Portland Health Care System, Portland, OR, Portland
Ages 18 to 75 · All sexes · Updated Aug 14, 2026 · NCT07226232

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

RecruitingPhase 3
  • Summit Headlands, Portland
Ages 18 to 75 · All sexes · Updated Aug 6, 2026 · NCT07412756

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • Providence Portland Medical Center, Portland
  • Providence Saint Vincent Medical Center, Portland
  • Kaiser Permanente Northwest, Portland
  • and 1 more
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

Implementation of Problem-Solving Treatment in Community Health Centers (PST-Aid)

Recruiting
  • OCHIN, Inc., Portland
Ages 18 and older · All sexes · Updated Sep 15, 2025 · NCT06494384

A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

RecruitingPhase 4
  • Clinical Research Site, Portland
Ages 18 to 65 · All sexes · Updated Jan 23, 2025 · NCT06223880

Reaching Out to Distressed Medical Residents, Fellows and Faculty

RecruitingHealthy volunteers welcome
  • Oregon Health and Science University, Portland
Ages 18 and older · All sexes · Updated Apr 30, 2024 · NCT02010866

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

Depression trials in other cities

Other studies in Portland

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.