🔎 Trials Near Me

Home › Depression › California › Los Angeles

Depression clinical trials in Los Angeles, CA

17 studies for Depression are looking for participants at sites in and around Los Angeles (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

RecruitingPhase 3
  • CalNeuro Research Group, Los Angeles
  • Lipov Medical Group, Los Angeles
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06793397

NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Los Angeles
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT06963021

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • Kaiser Permanente Los Angeles Medical Center, Los Angeles
  • Los Angeles General Medical Center, Los Angeles
  • USC / Norris Comprehensive Cancer Center, Los Angeles
  • and 1 more
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

RecruitingPhase 3
  • CalNeuro Research Group, Inc., Los Angeles
Ages 18 to 74 · All sexes · Updated Aug 3, 2026 · NCT06775379

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Los Angeles
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06966401

A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

RecruitingEarly phase 1
  • UCLA Semel Institute - Neuropsychiatric Institute (NPI), Los Angeles
Ages 50 to 95 · All sexes · Updated Jul 6, 2026 · NCT06906939

Health And Response: Digital Markers for Outcomes in Perinatal Depression Treatment Study

Recruiting
  • University of California, Los Angeles, Los Angeles
Ages 18 and older · Women · Updated Jul 6, 2026 · NCT07577947

Inflammatory and Glutamatergic Mechanisms of Sustained Threat in Adolescents With Depression

RecruitingObservational study
  • University of California, Los Angeles, Los Angeles
Ages 14 to 21 · All sexes · Updated May 29, 2026 · NCT05329441

Assessing Improvements in Mood and Sleep Trial

Recruiting
  • The Regents of the University of California, Los Angeles, Los Angeles
Ages 55 and older · All sexes · Updated May 19, 2026 · NCT06639477

Better Sleep Study

Recruiting
  • Children's Hospital Los Angeles, Los Angeles
Ages 12 to 18 · All sexes · Updated May 11, 2026 · NCT06139861

Training Reward Responsiveness Through Virtual Reality

RecruitingPhase 2
  • University of California, Los Angeles, Los Angeles
Ages 18 and older · All sexes · Updated May 7, 2026 · NCT07219875

Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease

RecruitingPhase 1/2
  • Children's Hospital Los Angeles, Los Angeles
Ages 14 to 21 · All sexes · Updated May 6, 2026 · NCT05685368

S.T.A.N.D. Alacrity Center Signature Project

Recruiting
  • East Los Angeles College, Los Angeles
Ages 18 to 40 · All sexes · Updated Feb 5, 2026 · NCT05591937

RCT for Latina Mental Health Using Web-Based Apps

RecruitingHealthy volunteers welcome
  • UCLA, Los Angeles
Ages 18 and older · Women · Updated Dec 22, 2025 · NCT06874790

Model-based Electrical Brain Stimulation

Recruiting
  • University of Southern California, Los Angeles
Ages 18 and older · All sexes · Updated Sep 22, 2025 · NCT05327387

Project 2: Optimizing Engagement and Outcomes in STAND Digital Therapy

Recruiting
  • East Los Angeles College, Los Angeles
Ages 18 to 40 · All sexes · Updated Jul 31, 2025 · NCT05908565

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

Depression trials in other cities

Other studies in Los Angeles

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.