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Prostate Cancer clinical trials in Orange, CA

14 studies for Prostate Cancer are looking for participants at sites in and around Orange (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

RecruitingPhase 3
  • UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT07200830

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

RecruitingPhase 2
  • UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06632977

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

RecruitingPhase 3
  • University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 0040), Orange
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

RecruitingPhase 3
  • University of California Irvine, Orange
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

RecruitingPhase 3
  • Univ Cali Irvine ALS Neuromuscular, Orange
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06855277

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

RecruitingPhase 3
  • University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 0006), Orange
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

RecruitingPhase 3
  • UC Irvine Health, Orange
Ages 18 and older · Men · Updated Sep 11, 2026 · NCT06056830

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

RecruitingPhase 3
  • UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer

RecruitingPhase 1
  • UCI Health Chao Family Comprehensive Cancer Center, Orange
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05997615

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

RecruitingPhase 3
  • UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

RecruitingPhase 2
  • Chao Family Comprehensive Cancer Center, University of California Irvine, Orange
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06580002

Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

RecruitingPhase 4
  • St. Joseph Hospital, Orange
Ages 18 to 100 · Men · Updated Jun 4, 2026 · NCT05803941

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Orange
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Orange

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.