Healthy volunteer studies in St. Louis, MO
108 studies at sites in and around St. Louis accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
- Saint Louis Heart and Vascular, St Louis
Dominantly Inherited Alzheimer Network (DIAN)
RecruitingObservational studyHealthy volunteers welcome
- Washington University in St. Louis School of Medicine, St Louis
A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults
RecruitingPhase 1Healthy volunteers welcome
- Saint Louis University Center for Vaccine Development, St Louis
A Study to Assess the Safety, Tolerability, and Immunogenicity of 3 Lots of a Multivalent Pneumococcal Conjugate Vaccine Administered to Adults
RecruitingPhase 3Healthy volunteers welcome
- Sundance Clinical Research, LLC, St Louis
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network
RecruitingObservational studyHealthy volunteers welcome
- Washington University in St. Louis, St Louis
A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age
RecruitingPhase 3Healthy volunteers welcome
- GSK Investigational Site, St Louis
- GSK Investigational Site, St Louis
Precision Supplemental Imaging in Women With Dense Breasts
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Efficacy of a Multi-level School Intervention for LGBTQ Youth
RecruitingHealthy volunteers welcome
- Washington University in St. Louis, St Louis
Study to Understand Novel Biomarkers in Researching Dementia
RecruitingObservational studyHealthy volunteers welcome
- Washington University School of Medicine, St Louis
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
RecruitingPhase 3Healthy volunteers welcome
- ACCOMPLISH-2 Research Site, St Louis
- ACCOMPLISH-2 Research Site, Hazelwood · 14 mi away
Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section
RecruitingHealthy volunteers welcome
- Washington University Hospital, St Louis
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
RecruitingPhase 3Healthy volunteers welcome
- Washington University School of Medicine, St Louis
- Sundance Clinical Research, St Louis
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
RecruitingObservational studyHealthy volunteers welcome
- Mercy Infusion Center - Chippewa, St Louis
- Mercy Hospital South, St Louis
- Missouri Baptist Medical Center, St Louis
- and 4 more
The Vanguard Study: Testing a New Way to Screen for Cancer
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
RecruitingHealthy volunteers welcome
- Mercy Infusion Center - Chippewa, St Louis
- Mercy Hospital South, St Louis
- Missouri Baptist Medical Center, St Louis
- and 4 more
Family Communications After Genetic Testing
RecruitingHealthy volunteers welcome
- Mercy Infusion Center - Chippewa, St Louis
- Mercy Hospital South, St Louis
- Missouri Baptist Medical Center, St Louis
- and 4 more
Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer
RecruitingHealthy volunteers welcome
- Mercy Infusion Center - Chippewa, St Louis
- Mercy Hospital South, St Louis
- Missouri Baptist Medical Center, St Louis
- and 4 more
PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis With 64Cu-NODAGA-CANF (Volunteer - Dosimetry Study)
RecruitingEarly phase 1Healthy volunteers welcome
- Washington University School of Medicine, St Louis
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
RecruitingPhase 4Healthy volunteers welcome
- St. Louis VA Medical Center, St Louis
- Washington University in St. Louis, St Louis
A Clinical Trial Investigating the Safety and Biological Activity of the Antibody BNT351 in Adults Living Without and With HIV
RecruitingPhase 1Healthy volunteers welcome
- Washington University, St Louis
The HOPE Biobank Resource (BMT CTN 2402 HOPE)
RecruitingObservational studyHealthy volunteers welcome
- St. Louis Children's, St Louis
- Washington University, St Louis
PREVENT ALL ALS Study
RecruitingObservational studyHealthy volunteers welcome
- Washington University, St Louis
ASSESS ALL ALS Study
RecruitingObservational studyHealthy volunteers welcome
- Washington University, St Louis
Cerebrovascular Reactivity Measurements With High-Density Diffuse Optical Tomography
RecruitingHealthy volunteers welcome
- Washington University in St. Louis, St Louis
Brain Organization, Development, and Response to Intervention in Individual Neonates
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
RecruitingPhase 1/2Healthy volunteers welcome
- Local Institution - 0030, St Louis
Light Therapy for Obsessive-compulsive Disorder (OCD)
RecruitingEarly phase 1Healthy volunteers welcome
- Washington University, St Louis
Implementation and Effectiveness of the BJC-Pink and Pearl Project on Lung Cancer Screening
RecruitingObservational studyHealthy volunteers welcome
- Barnes-Jewish Hospital West County, Creve Coeur · 12 mi away
Evaluating the Implementation and Effectiveness of the Pink and Pearl Campaign on Lung Cancer Screening at Christian Hospital
RecruitingHealthy volunteers welcome
- Barnes-Jewish Christian Hospital, St Louis
Maternal Oxygen Supplementation for Intrauterine Resuscitation
RecruitingHealthy volunteers welcome
- Barnes Jewish Hospital, St Louis
Role of KATP Channel Loss in Type 2 Diabetes
RecruitingHealthy volunteers welcome
- Washington University in St. Louis, St Louis
Advancing Biopsychosocial Care Training Initiative
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma
RecruitingObservational studyHealthy volunteers welcome
- Washington University School of Medicine, St Louis
This Study Involves a Positron Emission Tomography (PET) Scan Using a New Investigational Radioactive Tracer, [18F]-FZTA, to Detect Inflammation in the Brain. The Tracer Will be Tested in Healthy Younger Adults and Individuals With Multiple Sclerosis.
RecruitingObservational studyHealthy volunteers welcome
- Washington University in St. Louis, St Louis
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
RecruitingObservational studyHealthy volunteers welcome
- Washinton University in St. Louis, St Louis
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
RecruitingPhase 2/3Healthy volunteers welcome
- Washington University in St. Louis, St Louis
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
RecruitingPhase 2/3Healthy volunteers welcome
- Washington University in St. Louis, St Louis
Feasibility of HPV Self-Collection Kits for Cervical Cancer Screening
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
PSMA PET Combined With MRI for the Detection of PCa
RecruitingPhase 3Healthy volunteers welcome
- Washington University, St Louis
Motiva Implants® Post-Approval Study
RecruitingHealthy volunteers welcome
- Parkcrest Plastic Surgery, St Louis
Small Extracellular Vesicles and Insulin Action
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Comprehensive HHT Outcomes Registry of the United States (CHORUS)
RecruitingObservational studyHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Effect of Ketone Esters on Liver Fat Content and Metabolic Function
RecruitingPhase 2Healthy volunteers welcome
- Washington University School of Medicine, St Louis
Pain in Juvenile Arthritis
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Migraine in Adolescents
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Aging, Geriatric Syndromes and Clonal Hematopoiesis
RecruitingObservational studyHealthy volunteers welcome
- Washington University School of Medicine, St Louis
DORA and LP in Alzheimer's Disease Biomarkers
RecruitingPhase 2Healthy volunteers welcome
- Washington University in St. Louis, School of Medicine, St Louis
Endometriosis and Migraine
RecruitingObservational studyHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Sleep Trial to Prevent Alzheimer's Disease
RecruitingPhase 2Healthy volunteers welcome
- Washington University School of Medicine, St Louis
A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII Deficiency)
RecruitingPhase 1Healthy volunteers welcome
- Washington University School of Medicine, St Louis
Advanced SPinal Innovations With Robotics and Enabling Technology Registry
RecruitingObservational studyHealthy volunteers welcome
- St. Louis Children's Hospital, St Louis
Vagus Nerve Stimulation for Myelopathy
RecruitingHealthy volunteers welcome
- Washington University, St Louis
64Cu-LLP2A for Imaging Hematologic Malignancies
RecruitingEarly phase 1Healthy volunteers welcome
- Washington University School of Medicine, St Louis
Childhood Cancer Survivor Study
RecruitingObservational studyHealthy volunteers welcome
- St. Louis Children's Hospital/The Washington University, St Louis
Investigation of Inflammation in Alzheimer's Disease and Related Dementias (ADRD) Using [11C]-CS1P1
RecruitingObservational studyHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Beta Amyloid PET Imaging for Alzheimer Disease With [18F]-Fluselenamyl
RecruitingObservational studyHealthy volunteers welcome
- Washington University School of Medicine, St Louis
The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry
RecruitingObservational studyHealthy volunteers welcome
- Mercy Hospital St. Louis, St Louis
A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers
RecruitingHealthy volunteers welcome
- Sago St. Louis, St Louis
Galleri® in the Medicare Population.
RecruitingHealthy volunteers welcome
- Mercy Health St. Louis, St Louis
Late Onset Alzheimer's Disease
RecruitingObservational studyHealthy volunteers welcome
- Joanne Norton, St Louis
Parathyroid Tumor Clonal Status
RecruitingObservational studyHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Alzheimer"s Imaging Biomarkers in Obesity
RecruitingObservational studyHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Mindfulness to Enhance Cognitive Health in Latino Older Adults
RecruitingHealthy volunteers welcome
- Washington University, St Louis
Investigations of Dementia in Parkinson Disease
RecruitingObservational studyHealthy volunteers welcome
- Washington University in St. Louis, St Louis
Rejection Sensitivity and Puberty in Mental Health Vulnerability to Social Media Experiences in Early Adolescent Girls
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
PET Imaging CCR2 in Lung Inflammation
RecruitingEarly phase 1Healthy volunteers welcome
- Washington University School of Medicine, St Louis
Acellular Dermal Matrix Investigation in Breast Reconstruction
RecruitingHealthy volunteers welcome
- Washington University, St Louis
- Mercy Hospital, St Louis
NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits
RecruitingPhase 1Healthy volunteers welcome
- Washington University School of Medicine, St Louis
Study of Biodistribution, Metabolism, Excretion and Brain Uptake11C-M503
RecruitingEarly phase 1Healthy volunteers welcome
- Washington University in St. Louis, St Louis
Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone
RecruitingPhase 3Healthy volunteers welcome
- Saint Louis University, St Louis
A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)
RecruitingPhase 1Healthy volunteers welcome
- Saint Louis University Center for Vaccine Development ( Site 1031), St Louis
Early Intervention to Promote Cardiovascular Health of Mothers and Children
RecruitingHealthy volunteers welcome
- Washington University in St. Louis, St Louis
Neuroimaging of Parkinson's
RecruitingObservational studyHealthy volunteers welcome
- East Imaging Building, St Louis
Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study
RecruitingObservational studyHealthy volunteers welcome
- Mercy Hospital South, St Louis
- Mercy Hospital Saint Louis, St Louis
Spinal Cord Stimulation and Training
RecruitingHealthy volunteers welcome
- Washington University, St Louis
Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors
RecruitingPhase 3Healthy volunteers welcome
- Mercy Infusion Center - Chippewa, St Louis
- Mercy Hospital South, St Louis
- Missouri Baptist Medical Center, St Louis
- and 5 more
Mechanism of Ketogenic Diet-Induced Hypercholesterolemia
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
PET Imaging of MMP Activation in AAA: Clinical Component
RecruitingEarly phase 1Healthy volunteers welcome
- Washington University School of Medicine, St Louis
Dissecting Human Immune Responses to Infection With Influenza or SARS-CoV-2
RecruitingObservational studyHealthy volunteers welcome
- Washington University in Saint Louis Department of Emergency Medicine, Emergency Care Research Core, St Louis
Black and African Americans Connections to Parkinson's Disease (BLAAC PD)
RecruitingObservational studyHealthy volunteers welcome
- Washington University in St. Louis, St Louis
Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors
RecruitingObservational studyHealthy volunteers welcome
- Washington University School of Medicine, St Louis
A Study Evaluating the Safety and Efficacy of the 3M™ V.A.C. Peel and Place Dressing
RecruitingHealthy volunteers welcome
- Washington University - Barnes Jewish Hospital, St Louis
Intermuscular Coherence as a Biomarker for ALS
RecruitingObservational studyHealthy volunteers welcome
- Washington University Medical Center, St Louis
Beat Childhood Cancer Specimen Banking and Data Registry
RecruitingObservational studyHealthy volunteers welcome
- Cardinal Glennon Children's Hospital, St Louis
Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease
RecruitingObservational studyHealthy volunteers welcome
- Washington University in St. Louis, St Louis
Cardiac Structure and Function in MPS
RecruitingObservational studyHealthy volunteers welcome
- Saint Louis University, St Louis
Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial
RecruitingPhase 3Healthy volunteers welcome
- OSF Saint Anthony's Health Center, Alton · 18 mi away
The Role of Oxytocin in the Second Stage of Labor
RecruitingHealthy volunteers welcome
- Barnes Jewish Hospital, St Louis
Digital vs. Speculum Exams for PPROM
RecruitingHealthy volunteers welcome
- Barnes Jewish Hospital, St Louis
Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
RecruitingObservational studyHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science
RecruitingObservational studyHealthy volunteers welcome
- Washington University Medical Center/ St. Louis Children's Hospital, St Louis
Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in MDS
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
ColoSense Post-Approval Study
RecruitingObservational studyHealthy volunteers welcome
- Decentralized Study, St Louis
Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures
RecruitingObservational studyHealthy volunteers welcome
- Washington University, St Louis
Role of the Gut Microbiome in Complex Regional Pain Syndrome
RecruitingObservational studyHealthy volunteers welcome
- Washington University School of Medicine, St Louis
The DistaSense VITALS Study
RecruitingObservational studyHealthy volunteers welcome
- Clayton Sleep Institute, St Louis
Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in AML and MDS
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
MAP for Coaches: Translating Sports Injury Prevention Knowledge to Youth Sport Coaches
RecruitingHealthy volunteers welcome
- Olu Owoeye, St Louis
Mindfulness in Endometrial and Cervical Cancer
RecruitingHealthy volunteers welcome
- Saint Louis University, St Louis
Studying Health Outcomes After Treatment in Patients With Retinoblastoma
RecruitingObservational studyHealthy volunteers welcome
- Washington School of Medicine at St. Louis, St Louis
Characterizing the Human Airway Immune Response to FluMist Vaccination
RecruitingPhase 4Healthy volunteers welcome
- Washington University in Saint Louis School of Medicine Emergency Care and Research Core, St Louis
Cerebral Oxygen Metabolism in Children
RecruitingHealthy volunteers welcome
- Washington University of St. Louis, St Louis
PET Detection of CCR2 in Human Atherosclerosis
RecruitingPhase 1Healthy volunteers welcome
- Washington University CCIR, St Louis
LIMIT Trial - Lidocaine With Intramuscular Injection of Benzathine Penicillin G for Treponema Pallidum Treatment
RecruitingPhase 3Healthy volunteers welcome
- WashU Infectious Diseases Clinic, St Louis
APOL1 Genetic Testing in African Americans
RecruitingObservational studyHealthy volunteers welcome
- SSM Health Saint Louis University Hospital, St Louis
TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)
RecruitingObservational studyHealthy volunteers welcome
- Washington University, St Louis
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
RecruitingObservational studyHealthy volunteers welcome
- Washington University in St. Louis, St Louis
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.