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Alzheimer's Disease clinical trials in Irvine, CA

11 studies for Alzheimer's Disease are looking for participants at sites in and around Irvine (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)

RecruitingPhase 4
  • Progeny Psychiatric Clinic - Irvine, Irvine
Ages 50 and older · All sexes · Updated Sep 25, 2026 · NCT07633470

A Study of LY3439539 in Participants With Alzheimer's Disease

RecruitingPhase 1
  • Irvine Clinical Research, Irvine
Ages 50 to 85 · All sexes · Updated Sep 24, 2026 · NCT07598370

A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

RecruitingPhase 2
  • Irvine Clinical Research, Irvine
Ages 55 to 85 · All sexes · Updated Sep 22, 2026 · NCT07589595

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

RecruitingPhase 3
  • Irvine Center for Clinical Research, Irvine
Ages 50 to 90 · All sexes · Updated Sep 21, 2026 · NCT07177352

A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease

RecruitingPhase 1/2
  • Irvine Center for Clinical Research /ID# 277752, Irvine
Ages 50 to 90 · All sexes · Updated Sep 18, 2026 · NCT07599670

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

RecruitingPhase 3
  • Irvine Clinical Research, Irvine
Ages 60 to 85 · All sexes · Updated Sep 17, 2026 · NCT06976203

A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease

RecruitingPhase 3
  • Irvine Center for Clinical Research, Irvine
Ages 55 to 80 · All sexes · Updated Sep 10, 2026 · NCT07717411

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

RecruitingPhase 2
  • Irvine Clinical Research ( Site 1041), Irvine
Ages 50 to 85 · All sexes · Updated Aug 26, 2026 · NCT07033494

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

RecruitingPhase 3
  • Irvine Clinical Research, Irvine
Ages 55 and older · All sexes · Updated Jul 7, 2026 · NCT07602582

A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease

RecruitingPhase 2
  • Irvine Center for Clinical Research, Irvine
Ages 50 to 85 · All sexes · Updated Jun 26, 2026 · NCT07094516

Biomarker Exploration in Aging, Cognition and Neurodegeneration

RecruitingPhase 3Healthy volunteers welcome
  • University of California, Irvine, Irvine
Ages 60 and older · All sexes · Updated Jan 23, 2026 · NCT03860857

About Alzheimer's Disease

Alzheimer's disease is a brain disorder that slowly destroys memory and thinking skills. It's the most common cause of dementia among older adults.

More about Alzheimer's Disease on MedlinePlus

Alzheimer's Disease trials in other cities

Other studies in Irvine

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.