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Heart Failure clinical trials in Atlanta, GA

25 studies for Heart Failure are looking for participants at sites in and around Atlanta (within about 30 miles). Open a study to see who can join and how to contact the study team.

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ELEVATE-HFpEF Clinical Study

Recruiting
  • Emory University, Atlanta
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

RecruitingPhase 3
  • Research Site, Atlanta
  • Research Site, Atlanta
Ages 18 to 130 · All sexes · Updated Oct 2, 2026 · NCT06307652

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

RecruitingPhase 3
  • Atlanta Clinical Research Centers, Atlanta
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06935370

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

RecruitingPhase 3
  • Atlanta Clinical Research Centers, Atlanta
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06424288

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

RecruitingPhase 3
  • Research Site, Atlanta
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

RecruitingPhase 3
  • Grady Health System, Atlanta
  • Piedmont Atlanta Hospital, Atlanta
  • Emory Clinic, Atlanta
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT06736574

Alleviant ALLAY-HFrEF Study

Recruiting
  • Atlanta VA Health Care System, Decatur · 6 mi away
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06812533

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

RecruitingPhase 3
  • Piedmont Heart Institute, Atlanta
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

RecruitingPhase 3
  • Research Site, Atlanta
Ages 40 and older · All sexes · Updated Sep 15, 2026 · NCT06677060

A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

RecruitingPhase 3
  • CON-10022 Atlanta, GA Investigational Site, Atlanta
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06024746

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

RecruitingPhase 3
  • Atlanta, GA Investigative Site 10022, Atlanta
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • Piedmont Healthcare, Atlanta
  • Emory University, Atlanta
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

Recruiting
  • Piedmont Hospital, Atlanta
  • Emory University Hospital, Atlanta
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07069738

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

RecruitingPhase 2/3
  • Children's Healthcare of Atlanta - Arthur M. Blank Hospital ( Site 0001), Atlanta
29 Days – 17 Years · All sexes · Updated Aug 28, 2026 · NCT05714085

Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

Recruiting
  • Emory University Hospital, Atlanta
Ages 21 and older · All sexes · Updated Aug 25, 2026 · NCT05677100

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

RecruitingObservational study
  • Atlanta, Atlanta
All ages · All sexes · Updated Aug 20, 2026 · NCT00271180

LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2

RecruitingPhase 3
  • Tenax Investigational Site, Atlanta
Ages 18 to 85 · All sexes · Updated Aug 19, 2026 · NCT07288398

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

RecruitingPhase 3
  • Atlanta Center for Clinical Research_Atlanta, Atlanta
  • East Atlanta Cardiology, Conyers · 22 mi away
  • Hope Clin Res & Wellness, Conyers · 22 mi away
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

Alleviant ALLAY-HF Study

Recruiting
  • Atlanta VA Health Care System, Decatur · 6 mi away
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303

CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)

Recruiting
  • Atlanta VA Medical and Rehab Center, Decatur, GA, Decatur · 6 mi away
Ages 60 and older · All sexes · Updated Aug 14, 2026 · NCT05996328

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

RecruitingPhase 3
  • Emory University Hospital - Children's Healthcare of Atlanta Cardiology - Atlanta, Atlanta
Up to age 18 · All sexes · Updated Jun 29, 2026 · NCT07192952

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • Piedmont, Atlanta
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

RecruitingPhase 3
  • Emory University Hospital - Children's Healthcare of Atlanta Cardiology - Atlanta, Atlanta
6 Months – 17 Years · All sexes · Updated Jun 15, 2026 · NCT07188805

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • Piedmont Heart Institute, Atlanta
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)

Recruiting
  • Emory University Hospital, Atlanta
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06895070

About Heart Failure

Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.

More about Heart Failure on MedlinePlus

Heart Failure trials in other cities

Other studies in Atlanta

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.