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Obesity clinical trials in St. Louis, MO
25 studies for Obesity are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.
Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →
Effects of Pistachios on Postprandial Metabolic Responses in Adults With Overweight or Obesity
Recruiting
- Saint Louis University, St Louis
Two-Week Stair-Climbing Exercise Snacks and Metabolic Health in Adults With Overweight or Obesity: A Pilot Study
RecruitingHealthy volunteers welcome
- Saint Louis University, St Louis
A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide
RecruitingPhase 3
- Amicis Centers of Clinical Research, St Louis
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
RecruitingPhase 3
- Washington University School of Medicine, St Louis
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
RecruitingPhase 3
- Sundance Clinical Research, St Louis
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
RecruitingPhase 3
- Washington University School of Medicine, St Louis
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
RecruitingPhase 3
- Research Site, St Louis
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight
RecruitingPhase 3
- Clayton Sleep Institute - St. Louis - Tesson Ferry Road, St Louis
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
RecruitingPhase 3
- Saint Louis Heart and Vascular PC, St Louis
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
RecruitingPhase 3
- AURORA-1 Clinical Site, St Louis
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
RecruitingPhase 3
- AURORA-2 Clinical Site, St Louis
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
RecruitingPhase 3Healthy volunteers welcome
- ACCOMPLISH-2 Research Site, St Louis
- ACCOMPLISH-2 Research Site, Hazelwood · 14 mi away
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
RecruitingPhase 3
- Washington University, St Louis
- Amicis Centers of Clinical Research, St Louis
Digital InteGrated Behavioral treatmeNt for Comorbid obesITy and deprEssion Among Racial and Ethnic Adults Age 50 and Older
Recruiting
- Washington University School of Medicine in St Louis, St Louis
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
RecruitingPhase 3
- ACCOMPLISH-1 Research Site, St Louis
- ACCOMPLISH-1 Research Site, Hazelwood · 14 mi away
Advancing Biopsychosocial Care Training Initiative
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Role of KATP Channel Loss in Type 2 Diabetes
RecruitingHealthy volunteers welcome
- Washington University in St. Louis, St Louis
Evaluation of a Novel Technology to Support Tailored Health Behavior Counseling in Rural Primary Care Clinics
Recruiting
- Washington University in St. Louis, St Louis
Small Extracellular Vesicles and Insulin Action
RecruitingHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Adapting and Testing a Novel Digital Health Tool (PREVENT) to Improve Health Behavior Counseling and Cardiovascular Health in Rural Primary Care Clinics
Recruiting
- Washington University in St. Louis, St Louis
Effect of Ketone Esters on Liver Fat Content and Metabolic Function
RecruitingPhase 2Healthy volunteers welcome
- Washington University School of Medicine, St Louis
Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Therapy and Exercise Training in People With Obesity
Recruiting
- Washington University School of Medicine, St Louis
Alzheimer"s Imaging Biomarkers in Obesity
RecruitingObservational studyHealthy volunteers welcome
- Washington University School of Medicine, St Louis
Uterine Preservation Via Lifestyle Transformation
RecruitingPhase 2
- Washington University School of Medicine, St Louis
Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
RecruitingObservational studyHealthy volunteers welcome
- Washington University School of Medicine, St Louis
About Obesity
Read about the causes of obesity and find out what you can do to decrease your risk of its associated health issues.
More about Obesity on MedlinePlus
Obesity trials in other cities
- Houston, TX43 studies
- Chicago, IL41 studies
- New York City, NY40 studies
- San Antonio, TX40 studies
- Washington, DC33 studies
- Orlando, FL31 studies
- Dallas, TX30 studies
- Boston, MA28 studies
- Las Vegas, NV27 studies
- Miami, FL27 studies
- Baltimore, MD25 studies
- Jacksonville, FL25 studies
Other studies in St. Louis
- Non-Small Cell Lung Cancer73 studies
- Breast Cancer64 studies
- Metastatic Cancer54 studies
- Colorectal Cancer50 studies
- Prostate Cancer46 studies
- Cancer (all types)46 studies
- Lung Cancer39 studies
- Ovarian Cancer38 studies
- Pancreatic Cancer33 studies
- Endometrial Cancer29 studies
- Head and Neck Squamous Cell Carcinoma28 studies
- Heart Failure26 studies
From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.