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Obesity clinical trials in Knoxville, TN

10 studies for Obesity are looking for participants at sites in and around Knoxville (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

RecruitingPhase 3
  • New Phase Research and Development, Knoxville
  • Accellacare US Inc., d/b/a Accellacare of Knoxville, Knoxville
Ages 18 to 99 · All sexes · Updated Oct 5, 2026 · NCT07684235

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

RecruitingPhase 3
  • Accellacare of Knoxville, Knoxville
  • Cardiovascular Research of Knoxville North Knoxville Medical Center, Powell · 8 mi away
Ages 45 to 99 · All sexes · Updated Oct 5, 2026 · NCT07037433

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

RecruitingPhase 2
  • New Phase Research & Development /ID# 282131, Knoxville
  • Summit Medical Group- Halls Family Physicians /ID# 282435, Knoxville
Ages 18 to 75 · All sexes · Updated Oct 2, 2026 · NCT07752979

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

RecruitingPhase 3
  • Research Site, Knoxville
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

RecruitingPhase 3
  • Cardiovascular Research of Knoxville North Knoxville Medical Center, Powell · 8 mi away
  • Parkway Cardiology Associates, Oak Ridge · 20 mi away
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

RecruitingPhase 3
  • ACCOMPLISH-1 Research Site, Knoxville
Ages 18 to 79 · All sexes · Updated Aug 10, 2026 · NCT07654361

Daily Eating Patterns for Total Health Study

Recruiting
  • Healthy Eating and Activity Laboratory, Knoxville
Ages 25 to 60 · All sexes · Updated Jun 15, 2026 · NCT06455995

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With Obesity

RecruitingPhase 1
  • MBX Biosciences Investigational Site, Knoxville
Ages 18 to 65 · All sexes · Updated Jun 9, 2026 · NCT07142707

EBT Fruit and Vegetable Prescription

RecruitingHealthy volunteers welcome
  • Cherokee Health Systems, Dameron Avenue Pedatrics, Knoxville
Ages 4 to 10 · All sexes · Updated Jun 9, 2026 · NCT05028205

Relationship Between Aspirin Metabolism and Markers of Metabolic Dysfunction Among Pregnant Persons at Risk of Pre-eclampsia

RecruitingObservational study
  • University of Tennessee Medical Center, Knoxville
Ages 18 to 45 · Women · Updated Sep 10, 2025 · NCT06802861

About Obesity

Read about the causes of obesity and find out what you can do to decrease your risk of its associated health issues.

More about Obesity on MedlinePlus

Obesity trials in other cities

Other studies in Knoxville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.