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Head and Neck Cancer clinical trials in Orlando, FL

6 studies for Head and Neck Cancer are looking for participants at sites in and around Orlando (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Advent Health, Orlando
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • AdventHealth Medical Group Oncology Research at Celebration, Kissimmee · 16 mi away
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

RecruitingPhase 1
  • Advent Health Medical Group Radiation Oncology at Central Florida, Orlando
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07020117

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • AdventHealth Celebration, Celebration · 17 mi away
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

RecruitingPhase 1/2
  • Clermont Oncology Center, Clermont · 24 mi away
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

RecruitingPhase 1/2
  • Florida Cancer Specialists (from Sarah Canon research Institute), Orlando
Ages 18 and older · All sexes · Updated Feb 2, 2026 · NCT06319963

About Head and Neck Cancer

Head and neck cancer includes cancers of the mouth, nose, sinuses, salivary glands, throat, and lymph nodes. Read the different symptoms of each type.

More about Head and Neck Cancer on MedlinePlus

Head and Neck Cancer trials in other cities

Other studies in Orlando

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.