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Cancer (all types) clinical trials in Philadelphia, PA
59 studies for Cancer (all types) are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.
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Autoimmunity After Checkpoint Blockade
RecruitingObservational study
- University of Pennsylvania - Abramson Cancer Center, Philadelphia
A First-in-Human Study of KK2223 in Participants With Relapsed or Refractory T Cell Non-Hodgkin Lymphoma
RecruitingPhase 1
- University of Pennsylvania - Abramson Cancer Center, Philadelphia
A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors
RecruitingPhase 1
- GSK Investigational Site, Philadelphia
A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)
RecruitingPhase 1/2
- Children's Hospital of Philadelphia (CHOP) ( Site 4021), Philadelphia
A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
RecruitingPhase 1
- University of Pennsylvania, Philadelphia
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
RecruitingPhase 3
- Alliance Cancer Specialists - Media, Media · 12 mi away
First Time in Human (FTIH) Study to Investigate the Safety and Preliminary Activity of GSK5533524 Alone or in Combination in Adult Participants With Advanced Solid Tumors
RecruitingPhase 1
- GSK Investigational Site, Philadelphia
Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)
RecruitingPhase 3
- Hospital of the University of Pennsylvania Perelman Center for Advanced Medicine ( Site 0100), Philadelphia
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
RecruitingPhase 2
- Fox Chase Cancer Center, Philadelphia
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
RecruitingPhase 2/3
- University of Pennsylvania Perelman Center for Advanced Medicine, Philadelphia
- Thomas Jefferson University - Clinical Research Institute, Philadelphia
- Fox Chase Cancer Center, Philadelphia
A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
RecruitingPhase 1/2
- Children's Hospital of Philadelphia (CHOP) ( Site 3021), Philadelphia
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
RecruitingPhase 2
- University of Pennsylvania, Philadelphia
A Study to Investigate Safety and Effectiveness of Tacabrutideg (BGB-16673) in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies
RecruitingPhase 1/2
- Fox Chase Cancer Center, Philadelphia
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
RecruitingPhase 3
- Thomas Jefferson University, Sidney Kimmel Cancer Center - Clinical Trials Office, Philadelphia
- USO - Alliance Cancer Specialists, PC, Horsham · 16 mi away
A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
RecruitingObservational study
- University of Pennsylvania, Philadelphia
Lurbinectedin in FET-Fused Tumors
RecruitingPhase 1/2
- Children's Hospital of Philadelphia, Philadelphia
IMmunotherapy: Prospective Assessment of Cannabis Treatment in Cancer
RecruitingObservational study
- Thomas Jefferson University, Philadelphia
Project: Every Child for Younger Patients With Cancer
RecruitingObservational study
- Drexel University School of Medicine, Philadelphia
- Children's Hospital of Philadelphia, Philadelphia
- Saint Christopher's Hospital for Children, Philadelphia
- and 1 more
Abatacept in Immune Checkpoint Inhibitor Myocarditis
RecruitingPhase 3
- University of Pennsylvania, Philadelphia
Indirect Calorimetry-Guided Parenteral Nutrition Prescribing in Oncology Patients
Recruiting
- Fox Chase Cancer Center, Philadelphia
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
RecruitingPhase 1/2
- Abramson Cancer Center of the University of Pennsylvania, Philadelphia
FOG-001 in Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- University of Pennsylvania, Perelman School of Medicine, Philadelphia
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
RecruitingPhase 3
- University of Pennsylvania/Abramson Cancer Center, Philadelphia
- Pennsylvania Hospital, Philadelphia
- Thomas Jefferson University Hospital, Philadelphia
- and 5 more
Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).
RecruitingPhase 2
- Children's Hospital of Philadelphia, Philadelphia
Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)
RecruitingPhase 2
- Children's Hospital of Philadelphia, Philadelphia
Testing eSCCIP: An eHealth Psychosocial Intervention for English and Spanish Speaking Parents of Children With Cancer
RecruitingHealthy volunteers welcome
- Nemours Children's Health, Delaware, Wilmington · 25 mi away
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
RecruitingPhase 2
- Abramson Cancer Center at the University of Pennsylvania /ID# 275407, Philadelphia
Evaluation of Grief Therapy Approaches for Bereaved Parents
Recruiting
- Children's Hospital of Philadelphia (Data Collection Only), Philadelphia
Molecular Genetics Studies of Cancer Patients and Their Relatives
RecruitingObservational studyHealthy volunteers welcome
- Paoli Memorial Hospital, Paoli · 18 mi away
Childhood Cancer Survivor Study
RecruitingObservational studyHealthy volunteers welcome
- Children's Hospital of Philadelphia, Philadelphia
Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI
Recruiting
- Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, Philadelphia
Engaging M-health for Symptom Monitoring and Health Promotion for Women on Endocrine Therapy for Breast Cancer (EmSHAPE)
Recruiting
- Abramson Cancer Center at the University of Pennsylvania, Philadelphia
CT-95 in Advanced Cancers Associated With Mesothelin Expression
RecruitingPhase 1
- University of Pennsylvania, Philadelphia
- Context Investigational Site, Philadelphia
Synovial Sarcoma Registry / Biospecimen Repository
RecruitingObservational study
- Children's Hospital of Philadelphia, Philadelphia
Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors
RecruitingPhase 1
- Perelman Center for Advanced Medicine /ID# 250188, Philadelphia
Assessment of Multi-Level Interventions to Improve Adherence to Oral Medications in Cancer Patients
Recruiting
- Albert Einstein Healthcare Network, Philadelphia
ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors
RecruitingPhase 1/2
- University of Pennsylvania, Perelamn Center for Advanced Medicine, Philadelphia
- Thomas Jefferson University, Honickman Center, Philadelphia
- Fox Chase Cancer Center, Philadelphia
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
RecruitingPhase 2
- University of Pennsylvania (U Penn), Philadelphia
Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TGW101 in Participants With Advanced Solid Tumors
RecruitingPhase 1
- Fox Chase Cancer Center, Philadelphia
Massage Impact on Sleep in Pediatric Oncology
Recruiting
- Children's Hospital of Philadelphia, Philadelphia
A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors
RecruitingPhase 1
- Fox Chase Cancer Center, Philadelphia
Suprachoroidal Administration in Subjects With Metastases to the Choroid
RecruitingPhase 2
- Shields and Shields, PC, Philadelphia
Implementation of eHealth Delivery Alternatives for Cancer Genetic Testing for Hereditary Cancer (eREACH3)
RecruitingObservational studyHealthy volunteers welcome
- Abramson Cancer Center at the University of Pennsylvania, Philadelphia
TumorGlow Intraoperative Molecular Imaging (IMI)
RecruitingPhase 1/2
- University of Pennsylvania, Philadelphia
The Radiation Oncology Registry and Biosample Repository
RecruitingObservational study
- University of Pennsylvania, Philadelphia
Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors
RecruitingPhase 1/2
- University of Pennsylvania, Abramson Cancer Center, Philadelphia
- Fox Chase Cancer Center, Philadelphia
Re-Engaging AYA Survivors in Cancer-Related Healthcare
Recruiting
- Children's Hospital of Philadelphia, Philadelphia
- Penn Medicine, Philadelphia
From Screening to Support: A Multi-Method Analysis of HRSN Integration in Cancer Care
RecruitingObservational study
- Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia
Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)
RecruitingPhase 2
- Pennsylvania Oncology Hematolo /ID# 249637, Philadelphia
eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer
RecruitingHealthy volunteers welcome
- Abramson Cancer Center at the University of Pennsylvania, Philadelphia
CARE Study: Cancer, Asian Americans, and Relationship Enrichment
RecruitingHealthy volunteers welcome
- Fox Chase Cancer Center - Philadelphia, Philadelphia
Targeted Therapy to Increase RAI Uptake in Metastatic DTC
RecruitingObservational study
- Children's Hospital of Philadelphia, Philadelphia
Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer
RecruitingPhase 2
- Children's Hospital of Philadelphia, Philadelphia
Cannabis Use and Outcomes in Black and White Patients With Cancer
RecruitingObservational study
- Thomas Jefferson University, Philadelphia
- University of Pennsylvania, Philadelphia
Childhood Cancer Predisposition Study (CCPS)
RecruitingObservational study
- Children's Hospital of Philadelphia, Philadelphia
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
RecruitingObservational study
- Massive Bio SYNERGY-AI site, Philadelphia
A Prospective Registry to Enable Collection of Standardized Routine Care Oncology Patient Data
RecruitingObservational studyHealthy volunteers welcome
- Lankenau Medical Center, Paoli · 18 mi away
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
Recruiting
- Fox Chase Cancer Center, Philadelphia
Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer
RecruitingPhase 3
- Perelman Center for Advanced Medicine, Philadelphia
About Cancer (all types)
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More about Cancer (all types) on MedlinePlus
Cancer (all types) trials in other cities
- Houston, TX121 studies
- New York City, NY109 studies
- Boston, MA85 studies
- Los Angeles, CA74 studies
- Nashville, TN65 studies
- Washington, DC58 studies
- Durham, NC58 studies
- Chicago, IL51 studies
- Atlanta, GA49 studies
- Seattle, WA49 studies
- Arlington, VA48 studies
- St. Louis, MO46 studies
Other studies in Philadelphia
- Breast Cancer56 studies
- Non-Small Cell Lung Cancer51 studies
- Metastatic Cancer46 studies
- Prostate Cancer44 studies
- Colorectal Cancer44 studies
- Ovarian Cancer44 studies
- Lung Cancer36 studies
- Acute Myeloid Leukemia34 studies
- Heart Failure31 studies
- Endometrial Cancer28 studies
- Depression26 studies
- Pancreatic Cancer26 studies
From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.