Home › Heart Failure › New York › New York City
Heart Failure clinical trials in New York City, NY
51 studies for Heart Failure are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.
Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
Recruiting
- Weill Cornell Medical University, New York
- Rochester General Hospital, New York
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
RecruitingPhase 2
- Icahn Sch of Med-Mt Sinai Hosp, New York
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
RecruitingPhase 3
- Research Site, New York
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
RecruitingPhase 3
- NYU Langone Health, New York
- Mount Sinai Hospital-New York-52529, New York
A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
Recruiting
- Mount Sinai Morningside, New York
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
RecruitingPhase 3
- Mount Sinai Hospital-New York-52529, New York
- Icahn School of Medicine at Mount Sinai, New York
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
RecruitingPhase 3
- Research Site, New York
- Research Site, New York
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
RecruitingPhase 3
- Mount Sinai Hospital, New York
- Columbia University Medical Center / New York - Presbyterian, New York
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
RecruitingPhase 3
- Icahn School of Medicine at Mount Sinai, New York
Alleviant ALLAY-HFrEF Study
Recruiting
- Stony Brook Medicine, New York
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
RecruitingPhase 3
- Research Site, New York
The WiSE®-UP Study (The WiSE System Utilization & Performance Study)
RecruitingObservational study
- Weill Cornell Medicine, New York
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
Recruiting
- NYU Langone Health, New York
- Mount Sinai, New York
- Columbia University Irving Medical Center/ New York Presbyterian Hospital, New York
- and 1 more
A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
RecruitingPhase 2
- Local Institution - 154, New York
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
RecruitingPhase 2/3
- Columbia University Medical Center-Pediatric Cardiology ( Site 0016), New York
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
RecruitingPhase 2
- NYU Langone Health, New York
- Mount Sinai West, New York
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Recruiting
- Mount Sinai Morningside, New York
- Nyph/Cumc, New York
NORM-HF Pivotal Study
Recruiting
- Columbia University Irving Medical Center/ New York Presbyterian Hospital, New York
Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs
RecruitingObservational study
- Columbia University, New York
Improving TRansitions ANd OutcomeS for Heart FailurE Patients in Home Health CaRe (I-TRANSFER-HF)
RecruitingHealthy volunteers welcome
- VNS Health Partners in Care, New York
- Weill Cornell Medicine, New York
A Preliminary Study for INFORMED
RecruitingPhase 4
- Weill Cornell Medicine, New York
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
RecruitingObservational study
- New York, New York
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
RecruitingObservational study
- Mount Sinai Hospital, New York
Impella Reverse Remodeling in End-Stage Heart Failure
RecruitingObservational studyHealthy volunteers welcome
- Columbia University, New York
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
RecruitingPhase 3
- Tenax Investigational Site, New York
- Tenax Investigational Site, New York
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
RecruitingPhase 3
- NYU Langone Med Assoc Chelsea, New York
- NYU Langone Orthopedic Center, New York
- Mount Sinai Hosp at NYC, New York
- and 1 more
Alleviant ALLAY-HF Study
Recruiting
- New York University, New York
CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
Recruiting
- VA NY Harbor Healthcare System, New York, NY, New York
MediBeacon® Transdermal GFR System for the Evaluation of Kidney Function in Adults With Heart Failure
Recruiting
- Columbia University, New York
Improving Self-Care of Caregivers of Adults in Homecare With Heart Failure and Cognitive Impairment
Recruiting
- VNS Health, New York
Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System
RecruitingPhase 2
- Cuimc/Nyph, New York
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
Recruiting
- Mount Sinai West, New York
- Mount Sinai, New York
- Lenox Hill/ Northwell Health, New York
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
RecruitingPhase 3
- Icahn School of Medicine at Mount Sinai - Pediatric Cardiology, New York
- Columbia University Irving Medical Center - Pediatric Cardiology, New York
The CardioClip Study
Recruiting
- Columbia University Irving Medical Center / NewYork-Presbyterian Hospital, New York
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
RecruitingPhase 3
- Icahn School of Medicine at Mount Sinai - Pediatric Cardiology, New York
- Columbia University Irving Medical Center - Pediatric Cardiology, New York
Quantifying New Heart Muscle Cells
Recruiting
- Columbia University (Morgan Stanley Children's Hospital), New York
- Weill Cornell Medicine, New York
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Recruiting
- New York-Presbyterian/Columbia University Medical Center, New York
AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor
RecruitingObservational studyHealthy volunteers welcome
- Mount Sinai Hospital, New York
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
RecruitingPhase 3
- Icahn School of Med at Mt Sinai, New York
Intestinal Microbiota Transplantation in Patients With Chronic Heart Failure
RecruitingPhase 1
- Columbia University Irving Medical Center, New York
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Recruiting
- Northwell Staten Island, New York
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
Recruiting
- NYU Langone, New York
- Columbia University Medical Center/New York Presbyterian Hospital, New York
Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry
RecruitingObservational study
- Mount Sinai Fuster Heart Hospital, New York
His-Bundle Corrective Pacing in Heart Failure
Recruiting
- Weill Cornell Medical College, New York
- Mount Sinai Hospital, New York
Enhanced Nutritional Optimization in LVAD Trial
Recruiting
- Columbia University Medical Center, New York
Left vs Left Randomized Clinical Trial
Recruiting
- Weill Cornell Medicine, New York
- Icahn School of Medicine at Mount Sinai, New York
- Columbia University Medical Center/New York-Presbyterian Hospital (CUMC/NYPH), New York
Cardiogenic Shock Working Group Registry
RecruitingObservational study
- Columbia University Irving Medical Center, New York
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM
RecruitingObservational study
- Mount Sinai Morningside, New York
- The Mount Sinai Hospital, New York
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
RecruitingPhase 1
- NYU Langone Health, New York
Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
RecruitingObservational study
- New York University, New York
Use of ReDS Technology in Patients With Acute Heart Failure
Recruiting
- Mount Sinai Hospital, New York
About Heart Failure
Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.
More about Heart Failure on MedlinePlus
Heart Failure trials in other cities
- Boston, MA44 studies
- Dallas, TX42 studies
- Houston, TX36 studies
- Cleveland, OH33 studies
- Chicago, IL31 studies
- Philadelphia, PA31 studies
- San Francisco, CA29 studies
- Durham, NC26 studies
- St. Louis, MO26 studies
- Atlanta, GA25 studies
- Kansas City, MO25 studies
- Cincinnati, OH24 studies
Other studies in New York City
- Breast Cancer136 studies
- Non-Small Cell Lung Cancer121 studies
- Cancer (all types)109 studies
- Prostate Cancer103 studies
- Metastatic Cancer93 studies
- Colorectal Cancer78 studies
- Ovarian Cancer69 studies
- Lung Cancer60 studies
- Multiple Myeloma60 studies
- Pancreatic Cancer60 studies
- Endometrial Cancer52 studies
- Acute Myeloid Leukemia51 studies
From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.