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Cancer (all types) clinical trials in Columbus, OH

38 studies for Cancer (all types) are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of Mocertatug Rezetecan in Combination With Anti-cancer Therapies for Advanced Solid Tumors (BEHOLD-2)

RecruitingPhase 1/2
  • GSK Investigational Site, Columbus
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06796907

Met Non Small Cell Cancer Registry (MOMENT)

RecruitingObservational study
  • The Ohio State University Wexner Medical Center, Columbus
All ages · All sexes · Updated Oct 2, 2026 · NCT05376891

uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

RecruitingObservational study
  • Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05874921

Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care

RecruitingPhase 3
  • The Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07195591

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

RecruitingObservational study
  • The Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)

RecruitingPhase 2
  • The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C ( Site 0008), Columbus
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06979596

Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia

RecruitingPhase 3
  • Quetzal Site 8, Columbus
Ages 18 to 71 · All sexes · Updated Sep 23, 2026 · NCT07504458

Pan Tumor Rollover Study

RecruitingPhase 2
  • The Ohio University, Columbus
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT03899155

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

RecruitingPhase 2/3
  • Ohio State University Comprehensive Cancer Center (OSUCCC) - The James Cancer Hospital and Solove Research Institute, Columbus
All ages · All sexes · Updated Sep 18, 2026 · NCT03435796

Collection of Tissue Samples for Cancer Research

RecruitingObservational study
  • Ohio State University, Columbus
2 Months · All sexes · Updated Sep 16, 2026 · NCT00900198

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

RecruitingPhase 2
  • The Ohio State University, Department of Psychiatry, Columbus
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer -T, Columbus
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

RecruitingObservational study
  • Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Nationwide Children's Hospital, Columbus
  • Ohio State University Comprehensive Cancer Center, Columbus
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • The Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

RecruitingPhase 2
  • Nationwide Children's Hosp, Columbus
Ages 1 to 39 · All sexes · Updated Aug 7, 2026 · NCT05999994

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

RecruitingPhase 3
  • Ohio State University Comprehensive Cancer Center, Columbus
  • Columbus Oncology and Hematology Associates Inc, Columbus
  • Riverside Methodist Hospital, Columbus
  • and 8 more
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

RecruitingPhase 2
  • Nationwide Children's Hospital, Columbus
Ages 1 to 26 · All sexes · Updated Aug 4, 2026 · NCT07680439

The MedMemos Study: Promoting Adherence to Medications in Pediatric Bone Marrow Transplant Patients

Recruiting
  • Nationwide Children's Hospital, Columbus
Ages 0 to 12 · All sexes · Updated Jul 21, 2026 · NCT07718204

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

RecruitingPhase 1
  • The Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT07103018

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Stefanie Spielman Comprehensive Breast Center, Columbus
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

Childhood Cancer Survivor Study

RecruitingObservational studyHealthy volunteers welcome
  • Nationwide Children's Hospital, Columbus
All ages · All sexes · Updated Jun 17, 2026 · NCT01120353

Tempus Small Cell Lung Cancer Observational Study (Sculptor)

RecruitingObservational study
  • Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT05257551

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • The Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

RecruitingPhase 2
  • The Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT05145400

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

RecruitingPhase 1/2
  • The Ohio State University Wexner Medical Center, Columbus
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116

ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

RecruitingPhase 1/2
  • Ohio State University Wexner Medical Center Gynecologic Oncology at Mill Run, Columbus
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT03686124

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

RecruitingPhase 2
  • The Ohio State University, Stefanie Spielman Comprehensive Breast Center, Columbus
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT01042379

Precision Cancer Medicine for Advanced Cancer Through High-throughput Sequencing

RecruitingObservational study
  • Ohio State University Wexner Medical Center, Columbus
Ages 18 and older · All sexes · Updated Apr 8, 2026 · NCT02090530

Re-Engaging AYA Survivors in Cancer-Related Healthcare

Recruiting
  • Nationwide Children's Hospital, Columbus
Ages 15 to 29 · All sexes · Updated Feb 18, 2026 · NCT07138040

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

RecruitingPhase 2
  • The Ohio State University /ID# 230439, Columbus
Ages 18 and older · All sexes · Updated Feb 9, 2026 · NCT04895436

GEMINI-NSCLC: NSCLC Biomarker Study

RecruitingObservational study
  • Ohio State University, Columbus
  • OhioHealth Reseach Institute, Columbus
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT05236114

Preparing for Life and Academics for Young Childhood Cancer Survivors

Recruiting
  • Nationwide Children's Hospital, Columbus
All ages · All sexes · Updated Nov 17, 2025 · NCT06769334

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Columbus
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • The Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT06682793

Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays

RecruitingObservational study
  • Ohio State University, Columbus
  • OhioHealth Research Institute, Columbus
Ages 18 and older · All sexes · Updated May 6, 2025 · NCT05234177

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

Recruiting
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883

About Cancer (all types)

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More about Cancer (all types) on MedlinePlus

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Other studies in Columbus

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.