🔎 Trials Near Me

Home › Major Depressive Disorder › Florida › Jacksonville

Major Depressive Disorder clinical trials in Jacksonville, FL

12 studies for Major Depressive Disorder are looking for participants at sites in and around Jacksonville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

RecruitingPhase 3
  • Clinical NeuroScience Solutions Inc, Jacksonville
Ages 18 to 74 · All sexes · Updated Sep 25, 2026 · NCT06559306

A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 2
  • Clinical Neuroscience Solutions Inc. - Jacksonville, Jacksonville
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07621237

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

RecruitingPhase 3
  • CNS Healthcare, Jacksonville
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06793397

A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

RecruitingPhase 2
  • Seaport Investigator Site, Jacksonville
Ages 18 to 65 · All sexes · Updated Sep 14, 2026 · NCT07065240

A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

RecruitingPhase 3
  • Clinical Neuroscience Solutions, LLC (Jacksonville), Jacksonville
Ages 18 to 74 · All sexes · Updated Aug 10, 2026 · NCT07592689

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

RecruitingPhase 3
  • Clinical Neuroscience Solutions, Inc., Jacksonville
Ages 18 to 74 · All sexes · Updated Aug 3, 2026 · NCT06775379

Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

RecruitingPhase 2
  • Clinical Neuroscience Solutions, Inc., Jacksonville
Ages 18 to 64 · All sexes · Updated Aug 3, 2026 · NCT06547489

A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

RecruitingPhase 2
  • Clinical Neuroscience Solutions, Inc, Jacksonville
Ages 18 to 64 · All sexes · Updated Jul 27, 2026 · NCT07115329

Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

RecruitingPhase 3
  • Clinical Research Site, Jacksonville
Ages 18 to 65 · All sexes · Updated Jul 24, 2026 · NCT07484217

A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder

RecruitingPhase 2
  • Cns Healthcare - Jacksonville /ID# 277658, Jacksonville
Ages 18 to 65 · All sexes · Updated Jun 15, 2026 · NCT07276997

Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)

RecruitingPhase 2
  • Autobahn Site #101, Jacksonville
Ages 18 to 65 · All sexes · Updated Jan 20, 2026 · NCT06633016

A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

RecruitingPhase 4
  • Clinical Research Site, Jacksonville
Ages 18 to 65 · All sexes · Updated Jan 23, 2025 · NCT06223880

Major Depressive Disorder trials in other cities

Other studies in Jacksonville

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.