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Depression clinical trials in Birmingham, AL

8 studies for Depression are looking for participants at sites in and around Birmingham (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

RecruitingPhase 3
  • UAB Psychiatry and Behavioral Neurology, Birmingham
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06793397

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

RecruitingPhase 2
  • UAB, Psychiatry and Behavioral Neurology, Birmingham
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

RecruitingPhase 3
  • Birmingham VA Medical Center, Birmingham, AL, Birmingham
Ages 18 to 75 · All sexes · Updated Aug 14, 2026 · NCT07226232

Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents

RecruitingHealthy volunteers welcome
  • University of Alabama at Birmingham, Birmingham
Ages 10 to 24 · All sexes · Updated Jul 13, 2026 · NCT05437588

Investigating Dynamic Interactions in Distributed Cognitive Control Networks

RecruitingObservational study
  • University of Alabama at Birmingham, Birmingham
Ages 18 and older · All sexes · Updated Apr 29, 2026 · NCT05927974

MicroRNA Correlates of Childhood Maltreatment and Suicidality

RecruitingObservational studyHealthy volunteers welcome
  • University of Alabama at Birmingham, Birmingham
Ages 18 to 60 · All sexes · Updated Mar 30, 2026 · NCT04923685

Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus

Recruiting
  • University of Alabama Birmingham Hospital, Birmingham
Ages 12 to 22 · All sexes · Updated Oct 30, 2025 · NCT06232304

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

Depression trials in other cities

Other studies in Birmingham

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.