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Depression clinical trials in Little Rock, AR

10 studies for Depression are looking for participants at sites in and around Little Rock (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

RecruitingPhase 3
  • SanRo Clinical Research Group, Bryant · 15 mi away
Ages 18 to 74 · All sexes · Updated Sep 8, 2026 · NCT07076407

A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

RecruitingPhase 2
  • Draig Clinical Site, Little Rock
Ages 18 to 75 · All sexes · Updated Sep 2, 2026 · NCT07610473

A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression

RecruitingPhase 2
  • Draig Clinical Site, Little Rock
Ages 18 to 75 · All sexes · Updated Aug 26, 2026 · NCT07300969

NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Bryant · 15 mi away
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06911112

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • University of Arkansas for Medical Sciences, Little Rock
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

RecruitingPhase 3
  • Woodland International Research Group, Little Rock
Ages 18 to 74 · All sexes · Updated Aug 3, 2026 · NCT06775379

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Little Rock
  • Neurocrine Clinical Site, Bryant · 15 mi away
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06966401

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

RecruitingPhase 2
  • Pillar Clinical Research, LLC, Little Rock
  • Preferred Research Partners, Inc., Little Rock
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830

Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons

Recruiting
  • University of Arkansas for Medical Sciences, Little Rock
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT06923423

Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Little Rock
Ages 18 and older · All sexes · Updated Oct 29, 2025 · NCT06786624

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

Depression trials in other cities

Other studies in Little Rock

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.