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Depression clinical trials in Cambridge, MA

7 studies for Depression are looking for participants at sites in and around Cambridge (within about 30 miles). Open a study to see who can join and how to contact the study team.

Modulating Exercise Dosage to Improve Concussion Recovery

RecruitingPhase 1/2
  • Spaulding Rehabilitation Hospital, Cambridge
Ages 13 to 18 · All sexes · Updated Aug 31, 2026 · NCT05434130

Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder

RecruitingPhase 2
  • McLean Hospital, Belmont · 4 mi away
Ages 18 to 50 · All sexes · Updated Jun 25, 2026 · NCT05837104

Neural Correlates of Stress and Perceived Control in Adolescent Depression

RecruitingHealthy volunteers welcome
  • McLean Hospital, Belmont · 4 mi away
Ages 14 to 18 · Women · Updated May 19, 2026 · NCT04788524

Pharmacologic Augmentation of TMS for Depression With D-serine

RecruitingPhase 1
  • McLean Hospital, Belmont · 4 mi away
Ages 18 to 80 · All sexes · Updated May 15, 2026 · NCT06876129

Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression

RecruitingEarly phase 1
  • McLean Hospital, Belmont · 4 mi away
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT07560878

Early Life Stress and Depression: Molecular and Functional Imaging

RecruitingObservational studyHealthy volunteers welcome
  • McLean Hospital, Belmont · 4 mi away
Ages 20 to 32 · Women · Updated Dec 12, 2025 · NCT04713722

Stress Dynamics and Familial Risk for Depression in Female Adolescents

RecruitingHealthy volunteers welcome
  • McLean Hospital, Belmont · 4 mi away
Ages 13 to 15 · Women · Updated Oct 23, 2025 · NCT06816329

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

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Other studies in Cambridge

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.