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Depression clinical trials in Huntsville, AL

6 studies for Depression are looking for participants at sites in and around Huntsville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

RecruitingPhase 3
  • University of Alabama at Birmingham, Huntsville Regional Medical Campus, Huntsville
Ages 18 to 74 · All sexes · Updated Sep 8, 2026 · NCT07076407

NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Huntsville
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06911112

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Huntsville
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06966401

Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents

RecruitingHealthy volunteers welcome
  • UAB Huntsville Regional Medical Campus, Huntsville
Ages 10 to 24 · All sexes · Updated Jul 13, 2026 · NCT05437588

MicroRNA Correlates of Childhood Maltreatment and Suicidality

RecruitingObservational studyHealthy volunteers welcome
  • UAB Huntsville Regional Medical Campus, Huntsville
Ages 18 to 60 · All sexes · Updated Mar 30, 2026 · NCT04923685

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

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Other studies in Huntsville

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.