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Major Depressive Disorder clinical trials in Charleston, SC

6 studies for Major Depressive Disorder are looking for participants at sites in and around Charleston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

RecruitingPhase 3
  • Clinical Trials of South Carolina, Charleston
Ages 18 to 74 · All sexes · Updated Sep 25, 2026 · NCT06559306

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

Recruiting
  • Medical University of South Carolina, Charleston
Ages 22 to 70 · All sexes · Updated Aug 28, 2026 · NCT06423430

RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS

RecruitingHealthy volunteers welcome
  • Medical Univeristy of South Carolina, Charleston
Ages 18 to 65 · All sexes · Updated Jul 21, 2026 · NCT05977439

Mindfulness Training During Accelerated TMS for Depression

Recruiting
  • IOP, Charleston
  • Medical University of South Carolina (MUSC), Brain Stimulation Laboratory Institute of Psychiatry, Charleston
Ages 18 to 80 · All sexes · Updated Jun 17, 2026 · NCT07369557

REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

RecruitingPhase 3Healthy volunteers welcome
  • Lowcountry Center for Veterans Research, Charleston
Ages 18 and older · All sexes · Updated Apr 29, 2026 · NCT07280065

Dosing rTMS for Depression Post-SCI

Recruiting
  • Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
Ages 18 to 60 · All sexes · Updated Jan 14, 2026 · NCT05553353

Major Depressive Disorder trials in other cities

Other studies in Charleston

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.