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Heart Failure clinical trials in Los Angeles, CA

20 studies for Heart Failure are looking for participants at sites in and around Los Angeles (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

Recruiting
  • Cedars Sinai Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07069738

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

RecruitingPhase 3
  • Research Site, Los Angeles
  • Research Site, Los Angeles
Ages 18 to 130 · All sexes · Updated Oct 2, 2026 · NCT06307652

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

RecruitingPhase 3
  • Keck Medical Center of USC (outpatient clinic), Los Angeles
  • UCLA Medical Center Cardiovascular Clinic, Los Angeles
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT06736574

Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)

Recruiting
  • Keck Medicine of USC-Norris Healthcare Center - Transplant Clinic, Los Angeles
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07222813

Alleviant ALLAY-HFrEF Study

Recruiting
  • Keck Medical Center of USC, Los Angeles
  • University California Los Angeles Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06812533

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

RecruitingPhase 3
  • Research Site, Los Angeles
  • Research Site, Los Angeles
Ages 40 and older · All sexes · Updated Sep 15, 2026 · NCT06677060

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

RecruitingPhase 3
  • Los Angeles, CA Investigative Site 10089, Los Angeles
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • Cedars-Sinai Medical Center, Los Angeles
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

RecruitingPhase 2/3
  • The Regents of the University of California - Los Angeles (UCLA Pediatrics) ( Site 0002), Los Angeles
29 Days – 17 Years · All sexes · Updated Aug 28, 2026 · NCT05714085

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

RecruitingPhase 3
  • VAGrtrLosAngelesHlthcareSystem, Los Angeles
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

RecruitingObservational study
  • Cedars-Sinai Medical Center, Los Angeles
Ages 18 to 99 · All sexes · Updated Aug 11, 2026 · NCT06939751

Assessment of CCM in HF With Higher Ejection Fraction

Recruiting
  • USC Keck School of Medicine, Los Angeles
  • Cedars Sinai Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05064709

Staged Kidney Transplantation During Combined Heart/Kidney Transplantation

Recruiting
  • Cedars-Sinai Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06877169

The STOP-MED CTRCD Trial

RecruitingPhase 4
  • University of California, Los Angeles, Los Angeles
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06183437

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • USC, Los Angeles
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • Keck School of Medicine of USC, Los Angeles
  • UCLA Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)

Recruiting
  • Cedars Sinai Medical Center, Los Angeles
  • University of California Los Angeles, Los Angeles
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06895070

His-Bundle Corrective Pacing in Heart Failure

Recruiting
  • Cedars-Sinai Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Feb 9, 2026 · NCT05265520

Transplant of Redeemed Organs by Judicious Administration of New Direct-Acting Antivirals for Hepatitis-C Heart Recipients

RecruitingPhase 2
  • Cedars-Sinai Medical Center, Los Angeles
Ages 18 to 90 · All sexes · Updated Jan 22, 2026 · NCT03383419

About Heart Failure

Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.

More about Heart Failure on MedlinePlus

Heart Failure trials in other cities

Other studies in Los Angeles

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.