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Ovarian Cancer clinical trials in Orlando, FL

22 studies for Ovarian Cancer are looking for participants at sites in and around Orlando (within about 30 miles). Open a study to see who can join and how to contact the study team.

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Advent Health, Orlando
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • AdventHealth Medical Group Oncology Research at Celebration, Kissimmee · 16 mi away
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • AdventHealth Cancer Institute, Orlando
Ages 19 and older · All sexes · Updated Oct 1, 2026 · NCT06586957

Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer

RecruitingObservational study
  • Orlando Health, Orlando
Ages 18 and older · Women · Updated Sep 29, 2026 · NCT05051722

A Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

RecruitingPhase 2
  • Site 0308 - Advent Health, Orlando
  • Site 0241 - Florida Cancer Specialist - North, Altamonte Springs · 9 mi away
Ages 18 and older · Women · Updated Sep 29, 2026 · NCT05128825

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

RecruitingPhase 3
  • AdventHealth Orlando, Orlando
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213804

A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

RecruitingPhase 2
  • Orlando Health Cancer Institute Gynecologic Cancer Center - Orlando /ID# 278623, Orlando
Ages 18 and older · Women · Updated Sep 22, 2026 · NCT07059845

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

RecruitingPhase 1
  • Sara Cannon Research Institute Lake Nona, Orlando
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

RecruitingPhase 3
  • Orlando Health Winnie Palmer Hospital for Women and Babies ( Site 0085), Orlando
Ages 18 and older · Women · Updated Sep 17, 2026 · NCT07318558

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

RecruitingPhase 1/2
  • Florida Cancer Specialists - Lake Nona, Orlando
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07109726

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

RecruitingPhase 2
  • Advent Health Cancer Institute, Orlando
Ages 18 and older · Women · Updated Sep 14, 2026 · NCT06787612

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute - Lake Nona Florida, Orlando
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06293898

Phase 1 Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of ARR-002 in Advanced or Metastatic Ovarian or Endometrial Cancer.

RecruitingPhase 1
  • Sarah Cannon Research Institute at Florida Cancer Specialists, Orlando
Ages 18 and older · Women · Updated Sep 3, 2026 · NCT07755436

A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9

RecruitingPhase 1/2
  • Florida Cancer Specialists, Orlando
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07186842

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

RecruitingPhase 3
  • Orlando Health Cancer Institute, Orlando
  • Health Central, Ocoee · 10 mi away
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

RecruitingPhase 1
  • Florida Cancer Specialists, Orlando
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

RecruitingPhase 3
  • AdventHealth Cancer Institute, Orlando
Ages 18 and older · Women · Updated Jul 2, 2026 · NCT06819007

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

RecruitingPhase 1/2
  • Florida Cancer Specialists, Orlando
Ages 18 and older · All sexes · Updated Apr 1, 2026 · NCT05735080

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

RecruitingPhase 1
  • Dren Investigational Site, Orlando
Ages 18 and older · All sexes · Updated Jan 7, 2026 · NCT06999187

A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #8, Orlando
Ages 18 and older · All sexes · Updated Sep 5, 2025 · NCT05932862

About Ovarian Cancer

Ovarian cancer is a cancerous tumor that forms in the tissues of an ovary. The ovaries are a pair of female reproductive glands that make eggs and female hormones.

More about Ovarian Cancer on MedlinePlus

Ovarian Cancer trials in other cities

Other studies in Orlando

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.